Ppp1r12a

Gene Symbol Ppp1r12a
Entrez Gene 17931
Alt Symbol 1200015F06Rik, 5730577I22Rik, AA792106, AV099298, D10Ertd625e, Mypt1
Species Mouse
Gene Type protein-coding
Description protein phosphatase 1, regulatory (inhibitor) subunit 12A
Other Description myosin phosphatase target subunit 1|myosin phosphatase, target subunit 1|myosin phosphatase-targeting subunit 1|protein phosphatase 1 regulatory subunit 12A
Swissprots Q99NB6 Q8CBV2 Q05A74 Q9DBR7
Accessions BAB39108 EDL21699 EDL21700 EDL21702 EDL21703 Q9DBR7 AK004785 BAB23563 AK030460 AK035230 BAC28990 AK077739 AK139570 AK162199 BAE36787 AK182043 BC054076 BC125381 AAI25382 BC137630 AAI37631 XM_006513326 XP_006513389 XM_006513327 XP_006513390 XM_006513328 XP_006513391 XM_006513329 XP_006513392 NM_027892 NP_082168
Function Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN- dependent suppression of HIF1A activity (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000250}. Note=Along actomyosin filaments and stress fibers. {ECO:0000250}.
Tissue Specificity Expressed in striated and vascular smooth muscle, specificcally in type 2a fibers (at protein level). Expression levels are 20-30% higher in developed males than females (at protein level). {ECO:0000269|PubMed:20634291}.
Top Pathways Focal adhesion, Vascular smooth muscle contraction, Oxytocin signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway

MYPT1 CRISPR/Cas9 KO Plasmid (m) - sc-421809 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

MYPT1 HDR Plasmid (m) - sc-421809-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

MYPT1 Double Nickase Plasmid (m) - sc-421809-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

MYPT1 Double Nickase Plasmid (m2) - sc-421809-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

MYPT1 CRISPR Activation Plasmid (m) - sc-421809-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

MYPT1 CRISPR Activation Plasmid (m2) - sc-421809-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

MYPT1 Lentiviral Activation Particles (m) - sc-421809-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

MYPT1 Lentiviral Activation Particles (m2) - sc-421809-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

MYPT1 siRNA (m) - sc-37241 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

MYPT1 shRNA Plasmid (m) - sc-37241-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

MYPT1 shRNA (m) Lentiviral Particles - sc-37241-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

MISSION® esiRNA - EMU213881 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN39160 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND39160 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PPP1R12A siRNA (Mouse) - CRM2694 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse PPP1R12A (NM_027892.2) - SHH381012 from Creative biogene

Category siRNA
Species Reactivities Mouse

shRNA set against Mouse Ppp1r12a(NM_027892.2) - SHR133098 from Creative biogene

Category siRNA
Species Reactivities Mouse

PPP1R12A shRNA Plasmid (Mouse) - CHM2694 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse

PPP1R12A miRNA 3'UTR clone - MiUTR1M-09487 from Creative biogene

Species Reactivities Mouse
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