| Gene Symbol | Dcx |
|---|---|
| Entrez Gene | 13193 |
| Alt Symbol | Dbct |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | doublecortin |
| Other Description | doublecortex|doublin|lis-X|lissencephalin-X|lissencephaly, X-linked (doublecortin)|neuronal migration protein doublecortin |
| Swissprots | O88809 Q6E5A4 |
| Accessions | EDL14728 EDL14729 EDL14730 EDL14731 O88809 AB011678 BAA33387 AF045547 AAC31799 AK011597 AK014264 BAB29230 AK048410 BAC33328 AK049050 BAE43338 AK141942 AK164119 BAE37637 AK164139 AY560329 AAT58219 BC056391 AAH56391 BC057010 AAH57010 BC062974 AAH62974 CA315795 CB525395 CD350374 CD802698 CJ102759 XM_006528698 XP_006528761 NM_001110222 NP_001103692 NM_001110223 NP_001103693 NM_001110224 NP_001103694 NM_010025 NP_034155 |
| Function | Microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May participate along with PAFAH1B1/LIS-1 in a distinct overlapping signaling pathway that promotes neuronal migration (By similarity). {ECO:0000250}. |
| Subcellular Location | Cytoplasm {ECO:0000305}. Cell projection {ECO:0000250}. Note=Localizes at neurite tips. {ECO:0000250}. |
| Tissue Specificity | In neonatal tissues, highly expressed in brain, but not expressed in heart, liver, kidney and spleen. In adult tissues, faintly expressed in brain but not expressed in muscle, heart, lung, liver, spleen, intestine, kidney, testis and placenta. |
Mouse Dcx cDNA clone(NM_010025.2) - CDFL003486 from Creative Biomart
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Mouse DCX ORF clone(NM_010025.2) - CDCH385072 from Creative Biomart
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Mouse DCX ORF clone(NM_001110222.1) - CDCH385073 from Creative Biomart
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Mouse DCX ORF clone(NM_001110223.1) - CDCH385074 from Creative Biomart
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Mouse DCX ORF clone(NM_001110224.1) - CDCH385075 from Creative Biomart
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Mouse Dcx ORF Clone(NM_010025.2) - CDCL160705 from Creative Biomart
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Mouse Dcx ORF Clone(NM_001110222.1) - CDCR236490 from Creative Biomart
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Mouse Dcx ORF Clone(NM_001110222.1) - CDCR236491 from Creative Biomart
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Mouse Dcx ORF Clone(NM_001110223.1) - CDCR236492 from Creative Biomart
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Mouse Dcx ORF Clone(NM_001110223.1) - CDCR236493 from Creative Biomart
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Mouse Dcx ORF Clone(NM_001110224.1) - CDCR236494 from Creative Biomart
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Mouse Dcx ORF Clone(NM_010025.2) - CDCR248294 from Creative Biomart
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Mouse Dcx ORF Clone(NM_010025.2) - CDCR248295 from Creative Biomart
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Mouse Dcx ORF Clone(NM_001110223.1) - CDCR236492 from Creative biogene
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Mouse Dcx ORF clone (NM_010025.2) - CDCR054148 from Creative biogene
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Mouse Dcx ORF clone (NM_001110222.1) - CDCR054150 from Creative biogene
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Mouse Dcx ORF clone (NM_001110224.1) - CDCR054152 from Creative biogene
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Mouse Dcx cDNA Clone(NM_010025.2) - CDFL003486 from Creative biogene
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