| Gene Symbol |
INPP5F
|
| Entrez Gene |
22876
|
| Alt Symbol |
MSTP007, MSTPO47, SAC2, hSAC2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
inositol polyphosphate-5-phosphatase F
|
| Other Description |
Sac domain-containing inositol phosphatase 2|phosphatidylinositide phosphatase SAC2|sac domain-containing phosphoinositide 5-phosphatase 2
|
| Swissprots |
Q5W135 B3KRF1 Q9H3D9 D3DRD1 Q9NT51 Q9Y2H2 Q5W136 Q86U97 Q2T9J4 Q6NVY2
|
| Accessions |
EAW49379 EAW49380 EAW49381 Q9Y2H2 AB023183 BAA76810 AF109361 AAQ13509 AF113227 AAG39298 AI492073 AI783668 AK091448 BAG52363 AK123633 AK307758 AL137528 CAB70792 BC052367 AAH52367 BC067820 AAH67820 BC082755 AAH82755 BC111493 AAI11494 BF476150 CD642547 CN362016 DB636424 DN992317 H15412 XM_006717720 XP_006717783 XM_011539524 XP_011537826 XM_011539525 XP_011537827 XM_011539526 XP_011537828 XM_011539527 XP_011537829 XM_011539528 XP_011537830 XM_011539529 XP_011537831 NM_001243194 NP_001230123 NM_001243195 NP_001230124 NM_014937 NP_055752
|
| Function |
Inositol 5-phosphatase which acts on phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Hydrolyzes phosphatidylinositol 4,5- bisphosphate most effectively. Modulates AKT/GSK3B pathway by decreasing AKT and GSK3B phosphorylation. {ECO:0000269|PubMed:11274189, ECO:0000269|PubMed:17322895}.
|
| Tissue Specificity |
Ubiquitous. {ECO:0000269|PubMed:11274189}.
|
