Gene Symbol |
SCD5
|
Entrez Gene |
79966
|
Alt Symbol |
ACOD4, FADS4, HSCD5, SCD2, SCD4
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
stearoyl-CoA desaturase 5
|
Other Description |
acyl-CoA-desaturase 4|stearoyl-CoA 9-desaturase|stearoyl-CoA desaturase 4
|
Swissprots |
B2RPG0 Q86SK9 Q8NDS0 Q9H7D1 Q4W5Q5
|
Accessions |
AAY40977 EAX05902 EAX05903 EAX05904 EAX05905 Q86SK9 AF389338 AAP31443 AK024685 BAB14961 AL831891 CAD38567 BC004936 AAH04936 BC048971 AAH48971 BC137429 AAI37430 BC137432 AAI37433 CB155881 DB479400 DR763368 NM_001037582 NP_001032671 NM_024906 NP_079182
|
Function |
Fatty acid delta-9-desaturase that introduces a double bond in fatty acyl-coenzyme A at the delta-9 position. {ECO:0000269|PubMed:15907797}.
|
Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000269|PubMed:15907797}; Multi-pass membrane protein {ECO:0000269|PubMed:15907797}.
|
Tissue Specificity |
Detected in fetal brain, and at lower levels in fetal kidney. Detected in adult brain and pancreas, and at lower levels in kidney and lung. {ECO:0000269|PubMed:12727354, ECO:0000269|PubMed:15907797}.
|
Top Pathways |
PPAR signaling pathway, AMPK signaling pathway, Biosynthesis of unsaturated fatty acids, Fatty acid metabolism
|