| Gene Symbol | B3GALT5 |
|---|---|
| Entrez Gene | 10317 |
| Alt Symbol | B3GalT-V, B3GalTx, B3T5, GLCT5, beta-1,3-GalTase 5, beta-3-Gx-T5, beta3Gal-T5 |
| Species | Human |
| Gene Type | protein-coding |
| Description | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 |
| Other Description | UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 5|beta-1,3-galactosyltransferase 5|beta-3-galactosyltransferase 5|homolog of C. elegans Bt toxin resistance gene bre-5 |
| Swissprots | Q53Z19 A8KA86 Q9P1X6 D3DSI3 Q9NY96 Q2M3L5 Q9Y2C3 Q9P1X7 |
| Accessions | AAF07880 BAA94498 BAA94501 CAB90446 CAB91547 EAX09628 EAX09629 EAX09630 EAX09631 EAX09632 Q9Y2C3 AB020337 BAA77664 AK292951 BAF85640 AU100432 AW136254 AY372061 AAR08910 BC104862 AAI04863 BC104864 AAI04865 DQ645732 DQ645733 DQ645734 DQ645735 DQ645736 DQ645737 DQ645738 NM_001278650 NP_001265579 NM_006057 NP_006048 NM_033170 NP_149360 NM_033171 NP_149361 NM_033172 NP_149362 NM_033173 |
| Function | Catalyzes the transfer of Gal to GlcNAc-based acceptors with a preference for the core3 O-linked glycan GlcNAc(beta1,3)GalNAc structure. Can use glycolipid LC3Cer as an efficient acceptor. |
| Subcellular Location | Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. |
| Tissue Specificity | Expressed in stomach, jejunum, colon, pancreas, small intestine, testis and gastrointestinal and pancreatic cancer cell lines. Hardly detected in lung, liver, adrenal gland and peripheral blood leukocytes. |
| Top Pathways | Glycosphingolipid biosynthesis - globo series, Glycosphingolipid biosynthesis - lacto and neolacto series |