Gene Symbol | GUCA2A |
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Entrez Gene | 2980 |
Alt Symbol | GCAP-I, GUCA2, STARA |
Species | Human |
Gene Type | protein-coding |
Description | guanylate cyclase activator 2A (guanylin) |
Other Description | guanylate cyclase activator 2A (guanylin 2, intestinal, heat-stable)|guanylate cyclase-activating protein 1|guanylate cyclase-activating protein I|guanylin|prepro-guanylin |
Swissprots | Q02747 |
Accessions | CAC22258 EAX07168 Q02747 BC140428 AAI40429 BC156566 AAI56567 M95174 AAA58625 M97496 AAA35915 T28160 NM_033553 NP_291031 |
Function | Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. |
Subcellular Location | Secreted. |
Tissue Specificity | Highly expressed in ileum and colon. Found in plasma. |
HMW-Guanylin CRISPR/Cas9 KO Plasmid (h) - sc-407711 from Santa Cruz Biotechnology
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HMW-Guanylin HDR Plasmid (h) - sc-407711-HDR from Santa Cruz Biotechnology
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HMW-Guanylin Double Nickase Plasmid (h) - sc-407711-NIC from Santa Cruz Biotechnology
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HMW-Guanylin Double Nickase Plasmid (h2) - sc-407711-NIC-2 from Santa Cruz Biotechnology
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HMW-Guanylin CRISPR Activation Plasmid (h) - sc-407711-ACT from Santa Cruz Biotechnology
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HMW-Guanylin CRISPR Activation Plasmid (h2) - sc-407711-ACT-2 from Santa Cruz Biotechnology
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HMW-Guanylin Lentiviral Activation Particles (h) - sc-407711-LAC from Santa Cruz Biotechnology
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HMW-Guanylin Lentiviral Activation Particles (h2) - sc-407711-LAC-2 from Santa Cruz Biotechnology
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HMW-Guanylin siRNA (h) - sc-45332 from Santa Cruz Biotechnology
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HMW-Guanylin shRNA Plasmid (h) - sc-45332-SH from Santa Cruz Biotechnology
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HMW-Guanylin shRNA (h) Lentiviral Particles - sc-45332-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN9796 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9796 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01409 from Sigma-Aldrich
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GUCA2A siRNA (Human) - CRH2019 from Cohesion Biosciences
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GUCA2A - MBS8200131 from MyBioSource
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shRNA set against Human GUCA2A (NM_033553.2) - SHH309298 from Creative biogene
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shRNA set against Human GUCA2A(NM_033553.2) - SHH110063 from Creative biogene
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Human GUCA2A siRNA - orb262521 from Biorbyt
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GUCA2A shRNA Plasmid (Human) - CHH2019 from Cohesion Biosciences
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GUCA2A miRNA 3'UTR clone - MiUTR1H-04335 from Creative biogene
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