Gene Symbol | FXYD5 |
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Entrez Gene | 53827 |
Alt Symbol | DYSAD, HSPC113, IWU1, KCT1, OIT2, PRO6241, RIC |
Species | Human |
Gene Type | protein-coding |
Description | FXYD domain containing ion transport regulator 5 |
Other Description | FXYD domain-containing ion transport regulator 5|dysadherin|keratinocytes associated transmembrane protein 1 |
Swissprots | B7WNZ8 Q96DB9 Q9HC34 Q9P039 Q6UW44 |
Accessions | CBX47665 CBX47666 Q96DB9 AA044211 AA296696 AB072911 BAB83766 AF161462 AAF29077 AF177940 AAG09301 AI424071 AK304012 BAG64927 AY157582 AAO13166 AY358991 AAQ89350 BC009642 AAH09642 BC013834 BC018798 BG025158 BM839241 BQ183683 BQ440098 BQ941279 BT007343 AAP36007 BU164524 BU178888 DQ890585 ABM92202 DQ893747 ABM84673 XM_006723245 XP_006723308 XM_006723246 XP_006723309 XM_006723247 XP_006723310 NM_001164605 NP_001158077 NM_014164 NP_054883 NM_144779 NP_659003 NR_028406 |
Function | Involved in down-regulation of E-cadherin which results in reduced cell adhesion. Promotes metastasis. {ECO:0000269|PubMed:11756660}. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
Dysadherin CRISPR/Cas9 KO Plasmid (h) - sc-403279 from Santa Cruz Biotechnology
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Dysadherin HDR Plasmid (h) - sc-403279-HDR from Santa Cruz Biotechnology
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Dysadherin Double Nickase Plasmid (h) - sc-403279-NIC from Santa Cruz Biotechnology
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Dysadherin Double Nickase Plasmid (h2) - sc-403279-NIC-2 from Santa Cruz Biotechnology
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Dysadherin CRISPR Activation Plasmid (h) - sc-403279-ACT from Santa Cruz Biotechnology
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Dysadherin CRISPR Activation Plasmid (h2) - sc-403279-ACT-2 from Santa Cruz Biotechnology
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Dysadherin Lentiviral Activation Particles (h) - sc-403279-LAC from Santa Cruz Biotechnology
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Dysadherin Lentiviral Activation Particles (h2) - sc-403279-LAC-2 from Santa Cruz Biotechnology
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Dysadherin siRNA (h) - sc-45745 from Santa Cruz Biotechnology
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Dysadherin shRNA Plasmid (h) - sc-45745-SH from Santa Cruz Biotechnology
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Dysadherin shRNA (h) Lentiviral Particles - sc-45745-V from Santa Cruz Biotechnology
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FXYD5/Dysadherin RNAi - H00053827-R01 from Novus Biologicals
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FXYD5/Dysadherin RNAi - H00053827-R02 from Novus Biologicals
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MISSION® esiRNA - EHU141221 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9015 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9015 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01942 from Sigma-Aldrich
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FXYD5 siRNA (Human) - CRH9983 from Cohesion Biosciences
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FXYD5 - MBS8210852 from MyBioSource
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shRNA set against Human FXYD5 (NM_014164.5) - SHH297969 from Creative biogene
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Human FXYD5 siRNA - orb270485 from Biorbyt
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FXYD5 shRNA Plasmid (Human) - CHH9983 from Cohesion Biosciences
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FXYD5 miRNA 3'UTR clone - MiUTR3H-08642 from Creative biogene
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FXYD5 miRNA 3'UTR clone - MiUTR3H-08643 from Creative biogene
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FXYD5 miRNA 3'UTR clone - MiUTR3H-08644 from Creative biogene
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