| Gene Symbol |
CYP4B1
|
| Entrez Gene |
1580
|
| Alt Symbol |
CYPIVB1, P-450HP
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cytochrome P450, family 4, subfamily B, polypeptide 1
|
| Other Description |
cytochrome P450 4B1|cytochrome P450, subfamily IVB, polypeptide 1|cytochrome P450-HP|microsomal monooxygenase
|
| Swissprots |
Q8WWU9 Q8TD85 Q8WWV0 Q1HBI2 P13584 Q8WWF2
|
| Accessions |
ABF47106 EAX06888 EAX06889 EAX06890 EAX06891 P13584 AF491285 AAM09532 AK225576 AK225578 AK300921 BAG62553 AK300941 BAG62570 AK307715 AK313170 AY064484 AAL57719 AY064485 AAL57720 AY064486 AAL57721 AY151048 AAN72311 AY151049 AAN72312 BC017758 AAH17758 BM977596 DA380788 DQ892010 ABM82936 DQ895199 ABM86125 J02871 AAA35712 X16699 CAA34672 XM_011540831 XP_011539133 XM_011540832 XP_011539134 XM_011540833 XP_011539135 XM_011540834 XP_011539136 XR_946559 NM_000779 NP_000770 NM_001099772 NP_001093242
|
| Function |
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
|
| Subcellular Location |
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
|
| Tissue Specificity |
Detected in the liver and lung (at protein level). {ECO:0000269|PubMed:12695542}.
|