Dhfr

Gene Symbol Dhfr
Entrez Gene 24312
Alt Symbol Dhfr1
Species Rat
Gene Type protein-coding
Description dihydrofolate reductase
Other Description Dihydrofolate reductase 1 (active)
Swissprots Q920D2
Accessions EDM10015 Q920D2 AF318150 AAL11500 BC158583 AAI58584 NM_130400 NP_569084
Function Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA and that of DHFRL1 (By similarity). {ECO:0000250}.
Top Pathways Folate biosynthesis, One carbon pool by folate

CompoZr® Knockout ZFN Kit - CKOZFN52962 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND52962 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

DHFR siRNA (Rat) - CRR0087 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Rat

DHFR - MBS8223768 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Rat

shRNA set against Rat DHFR (NM_130400.2) - SHH277621 from Creative biogene

Category siRNA
Species Reactivities Rat

Rat DHFR siRNA - orb294936 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Rat

DHFR shRNA Plasmid (Rat) - CHR0087 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Rat
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