Gene Symbol | DNAH17 |
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Entrez Gene | 8632 |
Alt Symbol | DNAHL1, DNEL2 |
Species | Human |
Gene Type | protein-coding |
Description | dynein, axonemal, heavy chain 17 |
Other Description | axonemal beta dynein heavy chain 17|axonemal dynein heavy chain|axonemal dynein heavy chain-like protein 1|ciliary dynein heavy chain 17|ciliary dynein heavy chain-like protein 1|dynein heavy chain 17, axonemal|dynein light chain 2, axonemal|dynein, axonemal, heavy chain like 1|dynein, axonemal, heavy like 1|dynein, axonemal, heavy polypeptide 17 |
Swissprots | Q9UFH2 O00431 O15206 Q2M2Y1 Q6ZRQ2 Q8N7Q7 |
Accessions | EAW89527 EAW89528 Q9UFH2 AB290170 BAG06724 AJ000522 CAA04165 AK097776 BAC05170 AK126059 AK128065 AL122077 CAB59252 AL832652 BC105107 BC112284 XM_011525416 XP_011523718 XM_011525417 XP_011523719 XM_011525418 XP_011523720 XR_934583 NM_173628 NP_775899 NM_003727 |
Function | Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000305}. |
Tissue Specificity | Expressed in testis. {ECO:0000269|PubMed:9545504}. |
Top Pathways | Huntington's disease |
DNAH17 CRISPR/Cas9 KO Plasmid (h) - sc-409722 from Santa Cruz Biotechnology
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DNAH17 HDR Plasmid (h) - sc-409722-HDR from Santa Cruz Biotechnology
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DNAH17 Double Nickase Plasmid (h) - sc-409722-NIC from Santa Cruz Biotechnology
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DNAH17 Double Nickase Plasmid (h2) - sc-409722-NIC-2 from Santa Cruz Biotechnology
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DNAH17 CRISPR Activation Plasmid (h) - sc-409722-ACT from Santa Cruz Biotechnology
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DNAH17 CRISPR Activation Plasmid (h2) - sc-409722-ACT-2 from Santa Cruz Biotechnology
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DNAH17 Lentiviral Activation Particles (h) - sc-409722-LAC from Santa Cruz Biotechnology
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DNAH17 Lentiviral Activation Particles (h2) - sc-409722-LAC-2 from Santa Cruz Biotechnology
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DNAH17 siRNA (h) - sc-93768 from Santa Cruz Biotechnology
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DNAH17 shRNA Plasmid (h) - sc-93768-SH from Santa Cruz Biotechnology
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DNAH17 shRNA (h) Lentiviral Particles - sc-93768-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN7331 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7331 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01260 from Sigma-Aldrich
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shRNA set against Human DNAH17 (NM_173628.3) - SHH279093 from Creative biogene
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DNAH17 miRNA 3'UTR clone - MiUTR3H-11003 from Creative biogene
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