| Gene Symbol | Cyp2b12 |
|---|---|
| Entrez Gene | 29295 |
| Alt Symbol | Cyp2b15 |
| Species | Rat |
| Gene Type | protein-coding |
| Description | cytochrome P450, family 2, subfamily b, polypeptide 12 |
| Other Description | CYPIIB12|cytochrome P-450b type b|cytochrome P450 2B12|cytochrome P450, family 2, subfamily b, polypeptide 15 |
| Swissprots | P33272 |
| Accessions | P33272 X63545 CAA45107 NM_017156 NP_058852 |
| Function | Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. This isozyme seems responsible for metabolism of 2,2',4,4',5,5'-hexachlorobiphenyl. |
| Subcellular Location | Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein. |
| Tissue Specificity | Preputial gland, but not in liver. |
| Top Pathways | Steroid hormone biosynthesis, Chemical carcinogenesis, Arachidonic acid metabolism, Retinol metabolism |