| Gene Symbol |
Cyp2b12
|
| Entrez Gene |
29295
|
| Alt Symbol |
Cyp2b15
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
cytochrome P450, family 2, subfamily b, polypeptide 12
|
| Other Description |
CYPIIB12|cytochrome P-450b type b|cytochrome P450 2B12|cytochrome P450, family 2, subfamily b, polypeptide 15
|
| Swissprots |
P33272
|
| Accessions |
P33272 X63545 CAA45107 NM_017156 NP_058852
|
| Function |
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. This isozyme seems responsible for metabolism of 2,2',4,4',5,5'-hexachlorobiphenyl.
|
| Subcellular Location |
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
|
| Tissue Specificity |
Preputial gland, but not in liver.
|
| Top Pathways |
Steroid hormone biosynthesis, Chemical carcinogenesis, Arachidonic acid metabolism, Retinol metabolism
|