Gene Symbol |
ADAMDEC1
|
Entrez Gene |
27299
|
Alt Symbol |
M12.219
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
ADAM-like, decysin 1
|
Other Description |
ADAM DEC1|ADAM-like protein decysin-1|a disintegrin and metalloproteinase domain-like protein decysin-1|decysin|disintegrin protease
|
Swissprots |
B7ZAK5 O15204
|
Accessions |
EAW63607 O15204 AK300959 BAH13381 AK301007 BAH13391 AK311528 AK316320 BAH14691 AK316322 BAH14693 BC069582 AAH69582 BC074877 AAH74877 BC074878 AAH74878 DC387711 Y13323 CAA73764 XR_428306 NM_001145271 NP_001138743 NM_001145272 NP_001138744 NM_014479 NP_055294
|
Function |
May play an important role in the control of the immune response and during pregnancy. {ECO:0000250}.
|
Subcellular Location |
Secreted {ECO:0000250}.
|
Tissue Specificity |
Expressed highly in the small intestine and appendix, moderately in lymph node, mucosal lining of the colon, thymus, spleen and very weakly in the bone marrow. Predominantly expressed in dendritic cells (DC) of the germinal center. Weakly expressed in monocyte and highly expressed in macrophage. Absent in immature DC. {ECO:0000269|PubMed:14632642, ECO:0000269|PubMed:9271581}.
|