Gene Symbol | POU3F3 |
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Entrez Gene | 5455 |
Alt Symbol | BRN1, OTF8, brain-1, oct-8 |
Species | Human |
Gene Type | protein-coding |
Description | POU class 3 homeobox 3 |
Other Description | POU domain, class 3, transcription factor 3|brain-specific homeobox/POU domain protein 1|octamer-binding protein 8|octamer-binding transcription factor 8 |
Swissprots | Q4ZG25 P20264 P78379 |
Accessions | AAX88973 BAA19459 EAX01771 P20264 BC168366 AAI68366 CX873380 CX873394 NM_006236 NP_006227 |
Function | Transcription factor that acts synergistically with SOX11 and SOX4. Plays a role in neuronal development. Is implicated in an enhancer activity at the embryonic met- mesencephalic junction; the enhancer element contains the octamer motif (5'-ATTTGCAT-3') (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus. |
Tissue Specificity | Brain. |
Brn-1 CRISPR/Cas9 KO Plasmid (h) - sc-410950 from Santa Cruz Biotechnology
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Brn-1 HDR Plasmid (h) - sc-410950-HDR from Santa Cruz Biotechnology
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Brn-1 Double Nickase Plasmid (h) - sc-410950-NIC from Santa Cruz Biotechnology
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Brn-1 Double Nickase Plasmid (h2) - sc-410950-NIC-2 from Santa Cruz Biotechnology
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Brn-1 CRISPR Activation Plasmid (h) - sc-410950-ACT from Santa Cruz Biotechnology
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Brn-1 CRISPR Activation Plasmid (h2) - sc-410950-ACT-2 from Santa Cruz Biotechnology
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Brn-1 Lentiviral Activation Particles (h) - sc-410950-LAC from Santa Cruz Biotechnology
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Brn-1 Lentiviral Activation Particles (h2) - sc-410950-LAC-2 from Santa Cruz Biotechnology
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Brn-1 siRNA (h) - sc-29835 from Santa Cruz Biotechnology
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Brn-1 shRNA Plasmid (h) - sc-29835-SH from Santa Cruz Biotechnology
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Brn-1 shRNA (h) Lentiviral Particles - sc-29835-V from Santa Cruz Biotechnology
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POU3F3 RNAi - H00005455-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN17179 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17179 from Sigma-Aldrich
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POU3F3 siRNA (Human) - CRH3657 from Cohesion Biosciences
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shRNA set against Human POU3F3 (NM_006236.1) - SHH380088 from Creative biogene
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shRNA set against Human POU3F3(NM_006236.1) - SHR129964 from Creative biogene
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Human POU3F3 siRNA - orb264159 from Biorbyt
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POU3F3 shRNA Plasmid (Human) - CHH3657 from Cohesion Biosciences
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POU3F3 miRNA 3'UTR clone - MiUTR1H-08113 from Creative biogene
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