Gene Symbol | POU5F1B |
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Entrez Gene | 5462 |
Alt Symbol | OCT4-PG1, OCT4PG1, OTF3C, OTF3P1, POU5F1P1, POU5F1P4, POU5FLC20, POU5FLC8 |
Species | Human |
Gene Type | protein-coding |
Description | POU class 5 homeobox 1B |
Other Description | POU 5 domain protein|POU class 5 homeobox 1 pseudogene 1|POU domain transcription factor OCT4-pg1|POU domain transcription factor Oct-4|POU domain, class 5, transcription factor 1 pseudogene 1|octamer binding protein 3_like sequence|putative POU domain, class 5, transcription factor 1B |
Swissprots | E9LRQ4 E9LRB1 E9LRP8 E9LRM7 D5K9W0 E9LRH6 E9LRS3 E9LRQ0 E9LRN4 E9LRK5 D5K9X8 D5K9U6 D5K9X3 E9LRN5 D5K9S4 E9LRK4 D5K9X9 E9LRQ2 Q2VIK6 D5K9V4 Q9BZV7 D5K9T0 E9LRK7 D5K9S9 Q9BZV9 E9LRQ5 Q06416 D5K9V6 E9LRK8 D5K9X5 D5K9T1 D5K9T3 E9LRH5 D5K9X2 E9LRM9 E9LRB2 E9LRQ3 E9LRN2 D5K9W2 D5K9U3 E9LRH7 D5K9W7 |
Accessions | ABB92462 CAA77953 Q06416 AF268615 AAG53083 AF268618 AAG53085 DQ486513 ABF29403 FM177969 FM177970 FM177971 FM177972 FM177973 FM177974 FM177975 FM177976 FM177977 FM177978 FM177979 FM177980 FM177981 FM177982 GU480835 ADE48561 GU480840 ADE48566 GU480841 ADE48567 GU480842 ADE48568 GU480844 GU480845 ADE48570 GU480849 GU480850 GU480851 GU480864 ADE48580 GU480868 ADE48583 GU480878 ADE48591 GU480880 ADE48593 GU480883 ADE48596 GU480884 GU480885 GU480886 ADE48597 GU480889 ADE48599 GU480896 ADE48604 GU480899 GU480902 ADE48606 GU480905 ADE48609 GU480906 ADE48610 GU480908 ADE48612 GU480910 GU480911 ADE48614 GU480912 ADE48615 GU480913 ADE48616 HQ122710 ADW77351 HQ122711 ADW77352 HQ122712 ADW77353 HQ122713 ADW77354 HQ122714 ADW77355 HQ122715 HQ122716 ADW77356 HQ122717 ADW77357 HQ122718 ADW77358 HQ122719 ADW77359 HQ122720 HQ122721 ADW77360 HQ122749 ADW77385 HQ122750 ADW77386 HQ122751 ADW77387 HQ122752 ADW77388 HQ122781 ADW77415 HQ122782 ADW77416 HQ122783 ADW77417 HQ122784 ADW77418 HQ122785 ADW77419 HQ122786 ADW77420 HQ122787 ADW77421 HQ122788 ADW77422 HQ122789 ADW77423 HQ122790 ADW77424 HQ122816 ADW77444 HQ122817 ADW77445 HQ122818 ADW77446 HQ122819 ADW77447 HQ122820 ADW77448 HQ122821 ADW77449 HQ122822 ADW77450 HQ122823 ADW77451 HQ122824 ADW77452 HQ122825 ADW77453 HQ122826 ADW77454 HQ122827 ADW77455 HQ122841 ADW77467 HQ122842 ADW77468 HQ122843 ADW77469 HQ122844 ADW77470 HQ122845 ADW77471 HQ122846 ADW77472 HQ122847 HQ122848 ADW77473 HQ122849 ADW77474 HQ122850 HQ122851 ADW77475 HQ122852 ADW77476 HQ122853 ADW77477 HQ122854 ADW77478 HQ122855 ADW77479 HQ122856 ADW77480 HQ122857 ADW77481 HQ122863 HQ122864 ADW77487 HQ122865 ADW77488 HQ122866 ADW77489 HQ122867 ADW77490 HQ122868 ADW77491 HQ122869 ADW77492 HQ122870 ADW77493 HQ122871 ADW77494 HQ122872 HQ122873 HQ122874 ADW77495 HQ122875 HQ122876 ADW77496 HQ122877 ADW77497 HQ122878 ADW77498 HQ122879 ADW77499 HQ122880 ADW77500 HQ122881 ADW77501 HQ122882 ADW77502 HQ122883 ADW77503 HQ122884 ADW77504 HQ122885 ADW77505 HQ122886 ADW77506 HQ122887 ADW77507 HQ122891 ADW77511 HQ122892 ADW77512 HQ122893 ADW77513 HQ122894 HQ122895 ADW77514 HQ122896 HQ122897 HQ122898 ADW77515 HQ122899 HQ122900 ADW77516 HQ122901 HQ122902 ADW77517 HQ122903 ADW77518 NR_002304 NM_001159542 NP_001153014 |
Function | Shows weak transcriptional activator activity. {ECO:0000269|PubMed:18949397}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108, ECO:0000255|PROSITE-ProRule:PRU00530, ECO:0000269|PubMed:18949397}. |
Tissue Specificity | Detected at the mRNA level in several cancer tissues (breast, uterine cervix, lung, thyroid gland, esophagus, colon, urinary bladder, and glioma), but absent in normal tissues. {ECO:0000269|PubMed:16229821, ECO:0000269|PubMed:21341266}. |
Top Pathways | Signaling pathways regulating pluripotency of stem cells |
Anti-POU5F1B antibody - ab107643 from Abcam
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Anti-POU5F1B antibody - C-terminal - ab202393 from Abcam
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Anti-POU5F1B Antibody (aa292-326) - LS-C344503 from LifeSpan Bioscience
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Anti-POU5F1B Antibody (aa214-242) IHC-plus⢠- LS-B10480 from LifeSpan Bioscience
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Anti-POU5F1B Antibody (aa217-247, AP) - LS-C265419 from LifeSpan Bioscience
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Anti-POU5F1B Antibody (aa217-247, APC) - LS-C265420 from LifeSpan Bioscience
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Anti-POU5F1B Antibody (aa217-247, Biotin) - LS-C265421 from LifeSpan Bioscience
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Anti-POU5F1B Antibody (aa217-247, FITC) - LS-C265422 from LifeSpan Bioscience
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Anti-POU5F1B Antibody (aa217-247, Azide-free, HRP) - LS-C265423 from LifeSpan Bioscience
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Anti-POU5F1B Antibody (aa217-247, PE) - LS-C265424 from LifeSpan Bioscience
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Anti-POU5F1B Antibody (aa217-247) - LS-C323744 from LifeSpan Bioscience
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POU5F1P1 Antibody - NBP1-52164 from Novus Biologicals
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ANTI-P5F1B (C-TERM) antibody produced in rabbit - SAB1301745 from Sigma-Aldrich
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POU5F1B Antibody - C-terminal region (OAAB00838) - OAAB00838 from Aviva Systems Biology
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P5F1B-Antibody-C-term - AP10822b from Abgent, a WuXi AppTec company
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POU5F1B-Antibody-C-term - AP20933c from Abgent, a WuXi AppTec company
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POU5F1B-Antibody-N-term - AP21021a from Abgent, a WuXi AppTec company
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POU5F1B-Antibody-internal-region-near-C-Term - AF3204a from Abgent, a WuXi AppTec company
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POU5F1B-Antibody-C-term - AW5361 from Abgent, a WuXi AppTec company
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POU5F1B Antibody (OAEB00164) - OAEB00164 from Aviva Systems Biology
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P5F1B (C-term) antibody - AP53146PU-N from Acris Antibodies
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Anti-POU5F1B Antibody - AC21-2190 from Abcore
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Anti-POU5F1B Antibody (AMCA) - AC21-2190-01 from Abcore
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Anti-POU5F1B Antibody (AP) - AC21-2190-02 from Abcore
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Anti-POU5F1B Antibody (APC) - AC21-2190-03 from Abcore
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