| Gene Symbol |
RCC2
|
| Entrez Gene |
55920
|
| Alt Symbol |
TD-60
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
regulator of chromosome condensation 2
|
| Other Description |
RCC1-like protein TD-60|protein RCC2|telophase disk protein of 60 kDa
|
| Swissprots |
Q8IVL9 Q9BSN6 Q9P258 Q9NPV8
|
| Accessions |
EAW94838 EAW94839 Q9P258 AB040903 BAA95994 AJ421269 CAD13148 AK026005 AK126021 AL359612 CAB94882 BC004933 AAH04933 BC042141 AAH42141 BC053908 AAH53908 BC142946 AAI42947 BQ774471 CR991144 DR000303 NM_001136204 NP_001129676 NM_018715 NP_061185
|
| Function |
Required for completion of mitosis and cytokinesis. May function as a guanine nucleotide exchange factor for the small GTPase RAC1. {ECO:0000269|PubMed:12919680}.
|
| Subcellular Location |
Nucleus, nucleolus. Chromosome, centromere. Cytoplasm, cytoskeleton, spindle. Note=Appears in the nucleus at G2, then concentrates at the inner centromere region of chromosomes during prophase. Redistributes to the midzone of the mitotic spindle during anaphase. Here, the protein covers the entire equatorial diameter from cortex to cortex.
|