| Gene Symbol | PIK3C2G |
|---|---|
| Entrez Gene | 5288 |
| Alt Symbol | PI3K-C2-gamma, PI3K-C2GAMMA |
| Species | Human |
| Gene Type | protein-coding |
| Description | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma |
| Other Description | PTDINS-3-kinase C2 gamma|phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma|phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide|phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit gamma|phosphoinositide-3-kinase, class 2, gamma polypeptide|ptdIns-3-kinase C2 subunit gamma |
| Swissprots | A1L3U0 O75747 |
| Accessions | EAW96387 O75747 AI478164 AJ000008 CAA03853 BC130277 AAI30278 BC144133 BC144134 AAI44135 BX092808 XM_006719088 XP_006719151 XM_011520693 XP_011518995 XM_011520694 XP_011518996 XM_011520695 XP_011518997 XM_011520696 XP_011518998 XM_011520697 XP_011518999 XM_011520698 XP_011519000 XM_011520699 XP_011519001 XM_011520700 XP_011519002 XM_011520701 XP_011519003 XM_011520702 XP_011519004 XR_931307 NM_001288772 NP_001275701 NM_001288774 NP_001275703 NM_004570 NP_004561 |
| Function | Generates phosphatidylinositol 3-phosphate (PtdIns3P) and phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2) that act as second messengers. May play a role in SDF1A-stimulated chemotaxis (By similarity). {ECO:0000250}. |
| Subcellular Location | Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. |
| Tissue Specificity | Highly expressed in liver, prostate and testis. Lower levels in small intestine, kidney and pancreas. {ECO:0000269|PubMed:9878262}. |
| Top Pathways | Inositol phosphate metabolism, Phosphatidylinositol signaling system |
PI 3-kinase C2γ CRISPR/Cas9 KO Plasmid (h) - sc-406732 from Santa Cruz Biotechnology
|
||||||||
PI 3-kinase C2γ HDR Plasmid (h) - sc-406732-HDR from Santa Cruz Biotechnology
|
||||||||
PI 3-kinase C2γ Double Nickase Plasmid (h) - sc-406732-NIC from Santa Cruz Biotechnology
|
||||||||
PI 3-kinase C2γ Double Nickase Plasmid (h2) - sc-406732-NIC-2 from Santa Cruz Biotechnology
|
||||||||
PI 3-kinase C2γ CRISPR Activation Plasmid (h) - sc-406732-ACT from Santa Cruz Biotechnology
|
||||||||
PI 3-kinase C2γ CRISPR Activation Plasmid (h2) - sc-406732-ACT-2 from Santa Cruz Biotechnology
|
||||||||
PI 3-kinase C2γ Lentiviral Activation Particles (h) - sc-406732-LAC from Santa Cruz Biotechnology
|
||||||||
PI 3-kinase C2γ Lentiviral Activation Particles (h2) - sc-406732-LAC-2 from Santa Cruz Biotechnology
|
||||||||
PI 3-kinase C2γ siRNA (h) - sc-61338 from Santa Cruz Biotechnology
|
||||||||
PI 3-kinase C2γ shRNA Plasmid (h) - sc-61338-SH from Santa Cruz Biotechnology
|
||||||||
PI 3-kinase C2γ shRNA (h) Lentiviral Particles - sc-61338-V from Santa Cruz Biotechnology
|
||||||||
PIK3C2G RNAi - H00005288-R02 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU023691 from Sigma-Aldrich
|
||||||||
MISSION® siRNA - SIHK1646 from Sigma-Aldrich
|
||||||||
MISSION® siRNA - SIHK1647 from Sigma-Aldrich
|
||||||||
MISSION® siRNA - SIHK1648 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN16808 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16808 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR05346 from Sigma-Aldrich
|
||||||||
PIK3C2G siRNA (Human) - CRH3533 from Cohesion Biosciences
|
||||||||
shRNA set against Human PIK3C2G (NM_004570.4) - SHH375688 from Creative biogene
|
||||||||
PIK3C2G shRNA Plasmid (Human) - CHH3533 from Cohesion Biosciences
|
||||||||
PIK3C2G miRNA 3'UTR clone - MiUTR3H-10355 from Creative biogene
|