Gene Symbol | PRPH2 |
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Entrez Gene | 5961 |
Alt Symbol | AOFMD, AVMD, CACD2, DS, MDBS1, PRPH, RDS, RP7, TSPAN22, rd2 |
Species | Human |
Gene Type | protein-coding |
Description | peripherin 2 (retinal degeneration, slow) |
Other Description | peripherin 2, homolog of mouse|peripherin, photoreceptor type|peripherin-2|retinal degeneration slow protein|retinal peripherin|tetraspanin-22|tspan-22 |
Swissprots | Q6DK65 Q5TFH5 P23942 |
Accessions | AAA16958 AAB31191 EAX04098 P23942 BC074720 AAH74720 DQ426889 DQ579716 M62958 M73531 AAA60260 XR_427834 XR_926295 NM_000322 NP_000313 |
Function | May function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. It is essential for disk morphogenesis. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Retina (photoreceptor). In rim region of ROS (rod outer segment) disks. |
RDS CRISPR/Cas9 KO Plasmid (h) - sc-409674 from Santa Cruz Biotechnology
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RDS HDR Plasmid (h) - sc-409674-HDR from Santa Cruz Biotechnology
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RDS Double Nickase Plasmid (h) - sc-409674-NIC from Santa Cruz Biotechnology
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RDS Double Nickase Plasmid (h2) - sc-409674-NIC-2 from Santa Cruz Biotechnology
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RDS CRISPR Activation Plasmid (h) - sc-409674-ACT from Santa Cruz Biotechnology
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RDS CRISPR Activation Plasmid (h2) - sc-409674-ACT-2 from Santa Cruz Biotechnology
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RDS Lentiviral Activation Particles (h) - sc-409674-LAC from Santa Cruz Biotechnology
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RDS Lentiviral Activation Particles (h2) - sc-409674-LAC-2 from Santa Cruz Biotechnology
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RDS siRNA (h) - sc-40903 from Santa Cruz Biotechnology
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RDS shRNA Plasmid (h) - sc-40903-SH from Santa Cruz Biotechnology
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RDS shRNA (h) Lentiviral Particles - sc-40903-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU153891 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17483 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17483 from Sigma-Aldrich
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PRPH2 siRNA (Human) - CRH4034 from Cohesion Biosciences
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shRNA set against Human PRPH2 (NM_000322.4) - SHH383860 from Creative biogene
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Human PRPH2 siRNA - orb264536 from Biorbyt
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PRPH2 shRNA Plasmid (Human) - CHH4034 from Cohesion Biosciences
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PRPH2 miRNA 3'UTR clone - MiUTR3H-01995 from Creative biogene
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