RHOT1
| Gene Symbol | RHOT1 |
|---|---|
| Entrez Gene | 55288 |
| Alt Symbol | ARHT1, MIRO-1, MIRO1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | ras homolog family member T1 |
| Other Description | mitochondrial Rho (MIRO) GTPase 1|mitochondrial Rho GTPase 1|rac-GTP binding protein-like protein|ras homolog gene family, member T1 |
| Swissprots | Q6PJG1 Q9NUZ2 Q8IXJ7 Q9H9N8 Q8IXI2 Q8IW28 Q9H067 A4FVB6 B4DG48 J9JIH9 Q6NUR3 Q6P9F8 Q86UB0 A6NFV0 Q6YMW8 |
| Accessions | EAW80242 EAW80243 EAW80244 EAW80245 EAW80246 EAW80247 EAW80248 EAW80249 EAW80250 EAW80251 Q8IXI2 AA772711 AJ496730 CAD43139 AJ517412 CAD56956 AK001902 BAA91969 AK022695 BAB14185 AK294407 BAG57659 AL117543 AL136929 CAB66863 AM393207 CAL38085 AY094972 AAM15734 BC015698 AAH15698 BC029029 BC041114 AAH41114 BC051818 AAH51818 BC060781 AAH60781 BC068463 AAH68463 BC092401 BC110895 BC125104 AAI25105 BC125105 AAI25106 BC146694 AAI46695 CN352790 XM_011524969 XP_011523271 XM_011524970 XP_011523272 XM_011524971 XP_011523273 XM_011524972 XP_011523274 XM_011524973 XP_011523275 XM_011524974 XP_011523276 XM_011524975 XP_011523277 XM_011524976 XP_011523278 XR_934499 NM_001033566 NP_001028738 NM_001033567 NP_001028739 NM_001033568 NP_001028740 NM_001288754 NP_001275683 NM_001288755 NP_001275684 NM_001288758 NP_001275687 NM_018307 NP_060777 NR_110083 |
| Function | Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution. {ECO:0000269|PubMed:12482879, ECO:0000269|PubMed:16630562}. |
| Subcellular Location | Mitochondrion outer membrane {ECO:0000269|PubMed:12482879, ECO:0000269|PubMed:19528298}; Single-pass type IV membrane protein {ECO:0000269|PubMed:12482879, ECO:0000269|PubMed:19528298}. Note=Colocalizes with MGARP and RHOT2 at the mitochondria. |
| Tissue Specificity | Ubiquitously expressed. Expressed at high level in heart and skeletal muscle. {ECO:0000269|PubMed:12482879}. |
Rho T1 CRISPR/Cas9 KO Plasmid (h) - sc-401601 from Santa Cruz Biotechnology
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Rho T1 HDR Plasmid (h) - sc-401601-HDR from Santa Cruz Biotechnology
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Rho T1 Double Nickase Plasmid (h) - sc-401601-NIC from Santa Cruz Biotechnology
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Rho T1 Double Nickase Plasmid (h2) - sc-401601-NIC-2 from Santa Cruz Biotechnology
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Rho T1 CRISPR Activation Plasmid (h) - sc-401601-ACT from Santa Cruz Biotechnology
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Rho T1 CRISPR Activation Plasmid (h2) - sc-401601-ACT-2 from Santa Cruz Biotechnology
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Rho T1 Lentiviral Activation Particles (h) - sc-401601-LAC from Santa Cruz Biotechnology
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Rho T1 Lentiviral Activation Particles (h2) - sc-401601-LAC-2 from Santa Cruz Biotechnology
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Rho T1 siRNA (h) - sc-93809 from Santa Cruz Biotechnology
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Rho T1 shRNA Plasmid (h) - sc-93809-SH from Santa Cruz Biotechnology
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Rho T1 shRNA (h) Lentiviral Particles - sc-93809-V from Santa Cruz Biotechnology
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Rhot1 RNAi - H00055288-R06 from Novus Biologicals
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Rhot1 RNAi - H00055288-R07 from Novus Biologicals
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MISSION® esiRNA - EHU080821 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN18261 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18261 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR13064 from Sigma-Aldrich
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RHOT1 siRNA (Human) - CRJ0628 from Cohesion Biosciences
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Rhot1 RNAi - H00055288-R08 from Novus Biologicals
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Rhot1 RNAi - H00055288-R05 from Novus Biologicals
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RHOT1 - MBS8209658 from MyBioSource
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shRNA set against Human RHOT1 (NM_018307.3) - SHH395404 from Creative biogene
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shRNA set against Human RHOT1(NM_001033568.1) - SHR181016 from Creative biogene
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shRNA set against Human RHOT1(NM_018307.3) - SHR181182 from Creative biogene
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shRNA set against Human RHOT1(NM_001033566.1) - SHR181200 from Creative biogene
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