Gene Symbol | CCT2 |
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Entrez Gene | 10576 |
Alt Symbol | 99D8.1, CCT-beta, CCTB, HEL-S-100n, PRO1633, TCP-1-beta |
Species | Human |
Gene Type | protein-coding |
Description | chaperonin containing TCP1, subunit 2 (beta) |
Other Description | T-complex protein 1 subunit beta|T-complex protein 1, beta subunit|chaperonin containing t-complex polypeptide 1, beta subunit|chaperonin containing t-complex polypeptide 1, subunit 2|epididymis secretory sperm binding protein Li 100n |
Swissprots | Q14D36 B7Z7K4 P78371 B5BTY7 B7Z243 B7ZAT2 A8K402 Q6IAT3 |
Accessions | AAB67249 EAW97228 EAW97229 EAW97230 P78371 AA401491 AB451223 BAG70037 AB451346 BAG70160 AF026166 AAC98906 AF026293 AAC96012 AK290767 BAF83456 AK294307 BAH11729 AK297685 BAH12649 AK302157 BAH13640 AK316397 BAH14768 AK316408 BAH14779 BC113514 AAI13515 BC113516 AAI13517 BT019966 AAV38769 CB138063 CR457071 CAG33352 FJ224351 ACI46043 HQ258283 ADR83037 NM_001198842 NP_001185771 NM_006431 NP_006422 |
Function | Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin. {ECO:0000269|PubMed:20080638}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:20080638}. |
TCP-1 β siRNA (h) - sc-36622 from Santa Cruz Biotechnology
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TCP-1 β shRNA Plasmid (h) - sc-36622-SH from Santa Cruz Biotechnology
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TCP-1 β shRNA (h) Lentiviral Particles - sc-36622-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU012231 from Sigma-Aldrich
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MISSION® siRNA - SIHK0286 from Sigma-Aldrich
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MISSION® siRNA - SIHK0285 from Sigma-Aldrich
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MISSION® siRNA - SIHK0287 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5665 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5665 from Sigma-Aldrich
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CCT2 siRNA (Human) - CRH7196 from Cohesion Biosciences
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TCP1-beta RNAi - H00010576-R01 from Novus Biologicals
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CCT2 - MBS8213823 from MyBioSource
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shRNA set against Human CCT2 (NM_006431.2) - SHH258305 from Creative biogene
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shRNA set against Human CCT2(NM_006431.2) - SHG154027 from Creative biogene
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Human CCT2 siRNA - orb267698 from Biorbyt
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CCT2 shRNA Plasmid (Human) - CHH7196 from Cohesion Biosciences
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CCT2 miRNA 3'UTR clone - MiUTR1H-01833 from Creative biogene
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