FGFRL1
| Gene Symbol | FGFRL1 |
|---|---|
| Entrez Gene | 53834 |
| Alt Symbol | FGFR5, FHFR |
| Species | Human |
| Gene Type | protein-coding |
| Description | fibroblast growth factor receptor-like 1 |
| Other Description | FGF homologous factor receptor|FGF receptor-like protein 1|FGFR-5|FGFR-like protein|fibroblast growth factor receptor 5 |
| Swissprots | Q6PJN1 B2RAU9 Q8N441 Q9H4D7 Q9BXN7 |
| Accessions | EAW82615 Q8N441 AF279689 AAK26742 AF312678 AAK15273 AJ277437 CAC14171 AK000530 BAA91234 AK022597 AK172829 BAD18794 AK225486 AK314365 BAG36996 AV707425 AY358303 AAQ88670 BC002537 BC013955 BC015228 AAH15228 BC036769 AAH36769 BQ689625 DQ892417 ABM83343 DQ895631 ABM86557 XM_011513486 XP_011511788 XM_011513487 XP_011511789 NM_001004356 NP_001004356 NM_001004358 NP_001004358 NM_021923 NP_068742 |
| Function | Has a negative effect on cell proliferation. {ECO:0000250}. |
| Subcellular Location | Membrane {ECO:0000269|PubMed:12813049}; Single-pass type I membrane protein {ECO:0000269|PubMed:12813049}. Note=Predominantly localized in the plasma membrane but also detected in the Golgi and in secretory vesicles. |
| Tissue Specificity | Expressed preferentially in cartilaginous tissues and pancreas. Highly expressed in the liver, kidney, heart, brain and skeletal muscle. Weakly expressed in the lung, small intestine and spleen. {ECO:0000269|PubMed:11031111, ECO:0000269|PubMed:11267671, ECO:0000269|PubMed:11418238}. |
FGFR-5 CRISPR/Cas9 KO Plasmid (h) - sc-403773 from Santa Cruz Biotechnology
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FGFR-5 HDR Plasmid (h) - sc-403773-HDR from Santa Cruz Biotechnology
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FGFR-5 Double Nickase Plasmid (h) - sc-403773-NIC from Santa Cruz Biotechnology
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FGFR-5 Double Nickase Plasmid (h2) - sc-403773-NIC-2 from Santa Cruz Biotechnology
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FGFR-5 CRISPR Activation Plasmid (h) - sc-403773-ACT from Santa Cruz Biotechnology
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FGFR-5 CRISPR Activation Plasmid (h2) - sc-403773-ACT-2 from Santa Cruz Biotechnology
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FGFR-5 Lentiviral Activation Particles (h) - sc-403773-LAC from Santa Cruz Biotechnology
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FGFR-5 Lentiviral Activation Particles (h2) - sc-403773-LAC-2 from Santa Cruz Biotechnology
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FGFR-5 siRNA (h) - sc-39967 from Santa Cruz Biotechnology
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FGFR-5 shRNA Plasmid (h) - sc-39967-SH from Santa Cruz Biotechnology
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FGFR-5 shRNA (h) Lentiviral Particles - sc-39967-V from Santa Cruz Biotechnology
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FGF R5/FGFRL1 RNAi - H00053834-R05 from Novus Biologicals
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FGF R5/FGFRL1 RNAi - H00053834-R06 from Novus Biologicals
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FGF R5/FGFRL1 RNAi - H00053834-R04 from Novus Biologicals
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MISSION® esiRNA - EHU119331 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN8672 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8672 from Sigma-Aldrich
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FGFRL1 siRNA (Human) - CRH9989 from Cohesion Biosciences
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FGFRL1 - MBS8202275 from MyBioSource
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shRNA set against Human FGFRL1 (NM_021923.3) - SHH294725 from Creative biogene
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shRNA set against Human FGFRL1(NM_021923.3) - SHH058942 from Creative biogene
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shRNA set against Human FGFRL1(NM_001004356.2) - SHH058979 from Creative biogene
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Human FGFRL1 siRNA - orb270491 from Biorbyt
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FGFRL1 shRNA Plasmid (Human) - CHH9989 from Cohesion Biosciences
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FGFRL1 miRNA 3'UTR clone - MiUTR1H-03647 from Creative biogene
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