Gene Symbol | TUBB1 |
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Entrez Gene | 81027 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | tubulin, beta 1 class VI |
Other Description | beta tubulin 1, class VI|class VI beta-tubulin|tubulin beta-1 chain |
Swissprots | Q9H4B7 |
Accessions | EAW75447 Q9H4B7 AJ292757 CAC16605 BC033679 AAH33679 BI821931 JF432703 ADZ15920 NM_030773 NP_110400 |
Function | Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm, cytoskeleton {ECO:0000269|PubMed:18849486}. |
Tissue Specificity | Hematopoietic cell-specific. Major isotype in leukocytes, where it represents 50% of all beta-tubulins. {ECO:0000269|PubMed:20191564}. |
Top Pathways | Gap junction, Pathogenic Escherichia coli infection, Phagosome |
β1 Tubulin CRISPR/Cas9 KO Plasmid (h) - sc-400113 from Santa Cruz Biotechnology
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β1 Tubulin HDR Plasmid (h) - sc-400113-HDR from Santa Cruz Biotechnology
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β1 Tubulin Double Nickase Plasmid (h) - sc-400113-NIC from Santa Cruz Biotechnology
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β1 Tubulin Double Nickase Plasmid (h2) - sc-400113-NIC-2 from Santa Cruz Biotechnology
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β1 Tubulin CRISPR Activation Plasmid (h) - sc-400113-ACT from Santa Cruz Biotechnology
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β1 Tubulin CRISPR Activation Plasmid (h2) - sc-400113-ACT-2 from Santa Cruz Biotechnology
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β1 Tubulin Lentiviral Activation Particles (h) - sc-400113-LAC from Santa Cruz Biotechnology
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β1 Tubulin Lentiviral Activation Particles (h2) - sc-400113-LAC-2 from Santa Cruz Biotechnology
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β1 Tubulin siRNA (h) - sc-105000 from Santa Cruz Biotechnology
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β1 Tubulin shRNA Plasmid (h) - sc-105000-SH from Santa Cruz Biotechnology
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β1 Tubulin shRNA (h) Lentiviral Particles - sc-105000-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU112471 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22262 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22262 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR13173 from Sigma-Aldrich
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TUBB1 siRNA (Human) - CRJ2943 from Cohesion Biosciences
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beta I Tubulin RNAi - H00081027-R01 from Novus Biologicals
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TUBB1 - MBS8208643 from MyBioSource
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shRNA set against Human TUBB1 (NM_030773.3) - SHH437696 from Creative biogene
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Human Tubulin beta 1 siRNA - orb273444 from Biorbyt
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TUBB1 shRNA Plasmid (Human) - CHJ2943 from Cohesion Biosciences
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TUBB1 miRNA 3'UTR clone - MiUTR3H-12674 from Creative biogene
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