| Gene Symbol |
KCNN3
|
| Entrez Gene |
3782
|
| Alt Symbol |
KCa2.3, SK3, SKCA3, hSK3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3
|
| Other Description |
SKCa 3|potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3|small conductance calcium-activated potassium channel 3|small conductance calcium-activated potassium channel protein 3
|
| Swissprots |
Q9UGI6 Q8WXG7 Q86VF9 O43517 B1ANX0
|
| Accessions |
AAK15345 AAL40800 AAN46637 EAW53179 EAW53180 EAW53181 EAW53182 Q9UGI6 AA284005 AF031815 AAC26099 AF438203 AAL40801 AJ251016 CAB61331 AK310077 AW135188 AY049734 AAL10706 AY138900 AAN46636 AY258142 AAP45947 BC030100 BC042147 AAH42147 HQ448417 ADQ32897 Y08263 CAA69590 NM_001204087 NP_001191016 NM_002249 NP_002240 NM_170782 NP_740752
|
| Function |
Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin.
|
| Subcellular Location |
Membrane; Multi-pass membrane protein.
|
![Western Blot: KCNN3 Overexpression Lysate (Adult Normal) [NBP2-05209] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for KCNN3.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6406_KCNN3%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-05209-img0001.jpg)