| Gene Symbol |
NCOA4
|
| Entrez Gene |
8031
|
| Alt Symbol |
ARA70, ELE1, PTC3, RFG
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
nuclear receptor coactivator 4
|
| Other Description |
70 kDa AR-activator|70 kDa androgen receptor coactivator|NCoA-4|RET-activating gene ELE1|androgen receptor-associated protein of 70 kDa|ret fused
|
| Swissprots |
J3KQN8 B4E260 A8K8W5 Q13772 E9PAV7 Q14239
|
| Accessions |
EAW53686 EAW53687 EAW53688 EAW53689 Q13772 AB064669 BAB93520 AK129911 AK130612 AK292480 BAF85169 AK293978 BAG57348 AK302794 BAG63997 AK304123 BAG65022 AK310849 AK312325 BAG35247 AL162047 CAB82390 AM393327 CAL38205 AY425959 AAR07952 BC001562 AAH01562 BC012736 AAH12736 DA415606 DA860108 DB075100 DQ891598 ABM82524 DQ894792 ABM85718 GQ129251 ACT64385 GQ129252 ACT64386 L49399 AAC37591 X71413 CAA50536 X77548 CAA54673 NM_001145260 NP_001138732 NM_001145261 NP_001138733 NM_001145262 NP_001138734 NM_001145263 NP_001138735 NM_005437 NP_005428
|
| Function |
Enhances the androgen receptor transcriptional activity in prostate cancer cells. Ligand-independent coactivator of the peroxisome proliferator-activated receptor (PPAR) gamma. {ECO:0000269|PubMed:10347167}.
|
| Tissue Specificity |
Widely expressed. Also detected in adipose tissues and in different cell lines. Isoform Beta is only expressed in testis.
|
| Top Pathways |
Thyroid cancer
|