Gene Symbol | ARL6IP5 |
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Entrez Gene | 10550 |
Alt Symbol | DERP11, GTRAP3-18, HSPC127, JWA, PRAF3, addicsin, hp22, jmx |
Species | Human |
Gene Type | protein-coding |
Description | ADP-ribosylation factor-like 6 interacting protein 5 |
Other Description | ADP-ribosylation factor-like protein 6-interacting protein 5|ADP-ribosylation-like factor 6 interacting protein 5|ARL-6-interacting protein 5|JM5|PRA1 domain family 3|PRA1 family protein 3|aip-5|cytoskeleton related vitamin A responsive protein|cytoskeleton-related vitamin A-responsive protein|dermal papilla derived protein 11|dermal papilla-derived protein 11|glutamate transporter EAAC1-interacting protein|glutamate transporter EEAC1-associated protein|prenylated Rab acceptor protein 2|protein JWa|putative MAPK activating protein PM27|putative MAPK-activating protein PM27 |
Swissprots | Q5KU08 B2R6V5 O75915 Q53ES3 |
Accessions | EAW65473 EAW65474 O75915 AB014765 BAC66462 AB052638 BAD83603 AB097051 BAC77404 AF070523 AAC64360 AF115965 AAP97237 AF125530 AAF17224 AF161476 AAF29091 AK074612 BAG51976 AK223566 BAD97286 AK301637 BAG63118 AK303148 BAG64252 AK312731 BAG35602 AY102608 AAM28950 BC005143 AAH05143 BC020797 AAH20797 BC107899 BG483337 BU149630 NM_006407 NP_006398 |
Function | Regulates intracellular concentrations of taurine and glutamate. Negatively modulates SLC1A1/EAAC1 glutamate transport activity by decreasing its affinity for glutamate. May be involved in membrane traffic (By similarity). {ECO:0000250}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Also exists as a soluble form in the cytoplasm. Associated with microtubules (By similarity). {ECO:0000250}. |
JWA CRISPR/Cas9 KO Plasmid (h) - sc-406231 from Santa Cruz Biotechnology
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JWA HDR Plasmid (h) - sc-406231-HDR from Santa Cruz Biotechnology
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JWA Double Nickase Plasmid (h) - sc-406231-NIC from Santa Cruz Biotechnology
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JWA Double Nickase Plasmid (h2) - sc-406231-NIC-2 from Santa Cruz Biotechnology
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JWA CRISPR Activation Plasmid (h) - sc-406231-ACT from Santa Cruz Biotechnology
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JWA CRISPR Activation Plasmid (h2) - sc-406231-ACT-2 from Santa Cruz Biotechnology
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JWA Lentiviral Activation Particles (h) - sc-406231-LAC from Santa Cruz Biotechnology
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JWA Lentiviral Activation Particles (h2) - sc-406231-LAC-2 from Santa Cruz Biotechnology
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JWA siRNA (h) - sc-60874 from Santa Cruz Biotechnology
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JWA shRNA Plasmid (h) - sc-60874-SH from Santa Cruz Biotechnology
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JWA shRNA (h) Lentiviral Particles - sc-60874-V from Santa Cruz Biotechnology
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JWA RNAi - H00010550-R01 from Novus Biologicals
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MISSION® esiRNA - EHU041951 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3499 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3499 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09348 from Sigma-Aldrich
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ARL6IP5 siRNA (Human) - CRH7171 from Cohesion Biosciences
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ARL6IP5 - MBS8210119 from MyBioSource
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JWA CRISPR/Cas9 KO Plasmid (h2) - sc-406231-KO-2 from Santa Cruz Biotechnology
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JWA HDR Plasmid (h2) - sc-406231-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human ARL6IP5 (NM_006407.3) - SHH240310 from Creative biogene
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shRNA set against Human ARL6IP5(NM_006407.3) - SHG073195 from Creative biogene
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Human ARL6IP5 siRNA - orb267673 from Biorbyt
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ARL6IP5 shRNA Plasmid (Human) - CHH7171 from Cohesion Biosciences
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ARL6IP5 miRNA 3'UTR clone - MiUTR1H-00578 from Creative biogene
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