Gene Symbol | HES7 |
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Entrez Gene | 84667 |
Alt Symbol | SCDO4, bHLHb37 |
Species | Human |
Gene Type | protein-coding |
Description | hes family bHLH transcription factor 7 |
Other Description | bHLH factor Hes7|class B basic helix-loop-helix protein 37|hHes7|hairy and enhancer of split 7|transcription factor HES-7 |
Swissprots | F8VPC9 Q9BYE0 |
Accessions | EAW90092 Q9BYE0 AB049064 BAB39525 BC039887 BC156907 AAI56908 BI259590 BU620502 CA432402 XM_011524038 XP_011522340 XM_011524039 XP_011522341 XM_011524040 XP_011522342 XM_011524041 XP_011522343 XM_011524042 XP_011522344 NM_001165967 NP_001159439 NM_032580 NP_115969 |
Function | Transcriptional repressor. Represses transcription from both N box- and E box-containing promoters. May with HES1, cooperatively regulate somite formation in the presomitic mesoderm (PSM). May function as a segmentation clock, which is essential for coordinated somite segmentation (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000305}. |
HES7 CRISPR/Cas9 KO Plasmid (h) - sc-407096 from Santa Cruz Biotechnology
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HES7 HDR Plasmid (h) - sc-407096-HDR from Santa Cruz Biotechnology
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HES7 Double Nickase Plasmid (h) - sc-407096-NIC from Santa Cruz Biotechnology
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HES7 Double Nickase Plasmid (h2) - sc-407096-NIC-2 from Santa Cruz Biotechnology
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HES7 CRISPR Activation Plasmid (h) - sc-407096-ACT from Santa Cruz Biotechnology
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HES7 CRISPR Activation Plasmid (h2) - sc-407096-ACT-2 from Santa Cruz Biotechnology
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HES7 Lentiviral Activation Particles (h) - sc-407096-LAC from Santa Cruz Biotechnology
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HES7 Lentiviral Activation Particles (h2) - sc-407096-LAC-2 from Santa Cruz Biotechnology
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HES7 siRNA (h) - sc-75247 from Santa Cruz Biotechnology
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HES7 shRNA Plasmid (h) - sc-75247-SH from Santa Cruz Biotechnology
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HES7 shRNA (h) Lentiviral Particles - sc-75247-V from Santa Cruz Biotechnology
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HES7 RNAi - H00084667-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN9998 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9998 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04368 from Sigma-Aldrich
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HES7 siRNA (Human) - CRJ3568 from Cohesion Biosciences
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HES7 - MBS8231812 from MyBioSource
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shRNA set against Human Hes7 (NM_032580.3) - SHH311741 from Creative biogene
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HES7 CRISPR/Cas9 KO Plasmid (h2) - sc-407096-KO-2 from Santa Cruz Biotechnology
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HES7 HDR Plasmid (h2) - sc-407096-HDR-2 from Santa Cruz Biotechnology
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Human HES7 siRNA - orb274069 from Biorbyt
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HES7 shRNA Plasmid (Human) - CHJ3568 from Cohesion Biosciences
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HES7 miRNA 3'UTR clone - MiUTR4H-TG04156 from Creative biogene
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