| Gene Symbol |
COL11A1
|
| Entrez Gene |
1301
|
| Alt Symbol |
CO11A1, COLL6, STL2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
collagen, type XI, alpha 1
|
| Other Description |
collagen XI, alpha-1 polypeptide|collagen alpha-1(XI) chain
|
| Swissprots |
Q14034 P12107 D3DT73 Q9UIT5 B1ASK7 Q149N0 Q9UIT6 Q9UIT4 E9PCU0
|
| Accessions |
AAA79171 AAF04724 AAF04725 AAF04726 AAN86608 AAU88421 AAW47652 AAW47653 AAW47654 AAW47655 AAW47656 AAW65382 AAW65383 AAW65384 AAW65385 AAW65386 AAW65387 AAW65388 AAW65389 AAW65390 AAZ06348 CDM55401 CDM55582 EAW72908 EAW72909 EAW72910 EAW72911 EAW72912 EAW72913 P12107 AB208844 BAD92081 AK299025 BAG61102 AU118365 BC117697 AAI17698 BU159588 BX476821 CA448616 J04177 AAA51891 XM_011540719 XP_011539021 XM_011540720 XP_011539022 XM_011540721 XP_011539023 XR_946545 NM_001190709 NP_001177638 NM_001854 NP_001845 NM_080629 NP_542196 NM_080630 NP_542197
|
| Function |
May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils.
|
| Subcellular Location |
Secreted, extracellular space, extracellular matrix {ECO:0000255|PROSITE-ProRule:PRU00793}.
|
| Tissue Specificity |
Cartilage, placenta and some tumor or virally transformed cell lines. Isoforms using exon IIA or IIB are found in the cartilage while isoforms using only exon IIB are found in the tendon.
|
| Top Pathways |
Focal adhesion, ECM-receptor interaction, Amoebiasis, Protein digestion and absorption, PI3K-Akt signaling pathway
|