| Gene Symbol |
CADM2
|
| Entrez Gene |
253559
|
| Alt Symbol |
IGSF4D, NECL3, Necl-3, SynCAM 2, synCAM2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cell adhesion molecule 2
|
| Other Description |
immunoglobulin superfamily member 4D|immunoglobulin superfamily, member 4D|nectin-like 3|nectin-like protein 3|synaptic cell adhesion molecule 2
|
| Swissprots |
Q658Q7 Q8N3J6 G3XHN7 Q8IZP8 Q3KQY9 G3XHN8
|
| Accessions |
CAH68708 EAW68874 EAW68875 Q8N3J6 AB646739 BAK93302 AB646740 BAK93303 AB646741 BAK93304 AB646742 BAK93305 AB646743 BAK93306 AF538973 AAN16368 AK090787 AK094943 AK095545 AK295885 BAG58681 AL833049 CAH56314 AL834270 CAD38945 BC040985 BC063484 BC105999 AAI06000 BC112136 AAI12137 BC112138 AAI12139 BM674450 BX954585 XM_006713081 XP_006713144 XM_006713082 XP_006713145 NM_001167674 NP_001161146 NM_001167675 NP_001161147 NM_001256502 NP_001243431 NM_001256503 NP_001243432 NM_001256504 NP_001243433 NM_001256505 NP_001243434 NM_153184 NP_694854
|
| Function |
Adhesion molecule that engages in homo- and heterophilic interactions with the other nectin-like family members, leading to cell aggregation. Important for synapse organization, providing regulated trans-synaptic adhesion. Preferentially binds to oligodendrocytes. {ECO:0000269|PubMed:17967169}.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:17967169}; Single-pass type I membrane protein {ECO:0000269|PubMed:17967169}. Cell junction, synapse {ECO:0000269|PubMed:17967169}. Cell projection, axon {ECO:0000269|PubMed:17967169}. Note=Found in the axoplasm of myelinated axons.
|