Gene Symbol |
NDUFA5
|
Entrez Gene |
4698
|
Alt Symbol |
B13, CI-13KD-B, CI-13kB, NUFM, UQOR13
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
|
Other Description |
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa|NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5|NADH-ubiquinone oxidoreductase 13 kDa-B subunit|complex I 13kDa subunit B|complex I subunit B13|type I dehydrogenase|ubiquinone reductase
|
Swissprots |
Q16718 Q5H9R2 B2RD98 Q6IRX7
|
Accessions |
AAD21526 AAQ96854 EAW83587 EAW83588 EAW83589 EAW83590 EAW83591 EAW83592 EAW83593 Q16718 AK022209 BAB13985 AK315458 BAG37845 AV713284 BC000813 AAH00813 BC020821 AAH20821 BC070236 AAH70236 BC070237 AAH70237 BF670375 BF671339 BF790429 BG400546 BG611486 BT006695 AAP35341 CR933664 CAI45962 HG500559 U53468 AAB02224 U64028 AAB37259 W44870 NM_001282419 NP_001269348 NM_001282420 NP_001269349 NM_001282421 NP_001269350 NM_001282422 NP_001269351 NM_001291304 NP_001278233 NM_005000 NP_004991 NR_104168 NR_104169 NR_111925 NR_111926
|
Function |
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
|
Subcellular Location |
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
|
Tissue Specificity |
Expressed in all tissues examined with highest levels in heart, skeletal muscle and brain.
|
Top Pathways |
Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation
|