| Gene Symbol |
DAGLB
|
| Entrez Gene |
221955
|
| Alt Symbol |
DAGLBETA, KCCR13L
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
diacylglycerol lipase, beta
|
| Other Description |
DGL-beta|sn1-specific diacylglycerol lipase beta
|
| Swissprots |
A4D2P3 Q8NCG7 Q8WXE6 Q8TED3 Q6PIX3 B4DQU0 B3KV90 Q8N2N2 Q8N9S1
|
| Accessions |
CAF86385 CAH05554 EAL23721 EAW55033 EAW55034 EAW55035 EAW55036 EAW55037 Q8NCG7 AF450090 AAL47020 AK074210 BAB85017 AK074584 BAC11073 AK074744 BAC11175 AK075128 BAC11420 AK090943 BAG52250 AK091228 BAG52312 AK093958 BAC04258 AK122748 BAG53702 AK298910 BAG61018 AK298955 BAG61052 AK301087 BAG62690 AK301104 BAG62703 BC027603 AAH27603 CB528359 DC303993 DC304654 DQ590655 F17444 NM_001142936 NP_001136408 NM_139179 NP_631918
|
| Function |
Catalyzes the hydrolysis of diacylglycerol (DAG) to 2- arachidonoyl-glycerol (2-AG), the most abundant endocannabinoid in tissues. Required for axonal growth during development and for retrograde synaptic signaling at mature synapses. {ECO:0000269|PubMed:14610053}.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:14610053}; Multi-pass membrane protein {ECO:0000269|PubMed:14610053}.
|
| Top Pathways |
Retrograde endocannabinoid signaling
|