Gene Symbol | TLCD1 |
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Entrez Gene | 116238 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | TLC domain containing 1 |
Other Description | TLC domain-containing protein 1|calfacilitin |
Swissprots | A8MYP9 Q96CP7 |
Accessions | EAW51133 EAW51134 Q96CP7 BC014072 AAH14072 BF478215 BX106421 CA453962 EU831756 ACE87274 EU831834 ACE86593 JF432650 ADZ15867 XM_006721671 XP_006721734 XM_011524278 XP_011522580 NM_001160407 NP_001153879 NM_138463 NP_612472 |
Function | Calcium channel facilitator that increases calcium flux by generating a larger window current and slowing inactivation of the L-type CACNA1C/CaV1.2 channel. Regulation of intracellular calcium by Calfacilitin is required for neural plate formation (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
TLCD1 CRISPR/Cas9 KO Plasmid (h) - sc-414089 from Santa Cruz Biotechnology
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TLCD1 HDR Plasmid (h) - sc-414089-HDR from Santa Cruz Biotechnology
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TLCD1 Double Nickase Plasmid (h) - sc-414089-NIC from Santa Cruz Biotechnology
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TLCD1 Double Nickase Plasmid (h2) - sc-414089-NIC-2 from Santa Cruz Biotechnology
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TLCD1 CRISPR Activation Plasmid (h) - sc-414089-ACT from Santa Cruz Biotechnology
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TLCD1 CRISPR Activation Plasmid (h2) - sc-414089-ACT-2 from Santa Cruz Biotechnology
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TLCD1 Lentiviral Activation Particles (h) - sc-414089-LAC from Santa Cruz Biotechnology
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TLCD1 Lentiviral Activation Particles (h2) - sc-414089-LAC-2 from Santa Cruz Biotechnology
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TLCD1 siRNA (h) - sc-93906 from Santa Cruz Biotechnology
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TLCD1 shRNA Plasmid (h) - sc-93906-SH from Santa Cruz Biotechnology
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TLCD1 shRNA (h) Lentiviral Particles - sc-93906-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU051941 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21387 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21387 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00490 from Sigma-Aldrich
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TLCD1 siRNA (Human) - CRJ4502 from Cohesion Biosciences
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TLCD1 - MBS8210401 from MyBioSource
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TLCD1 shRNA Plasmid (Human) - CHJ4502 from Cohesion Biosciences
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