| Gene Symbol |
MXD1
|
| Entrez Gene |
4084
|
| Alt Symbol |
BHLHC58, MAD, MAD1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
MAX dimerization protein 1
|
| Other Description |
MAX-binding protein|antagonizer of myc transcriptional activity|max dimerization protein 1|max dimerizer 1
|
| Swissprots |
Q05195 B2R6V8 Q6FI41 B7ZLI6 D6W5G2
|
| Accessions |
AAY14867 EAW99838 EAW99839 Q05195 AK301088 BAH13406 AK312734 BAG35605 BC036402 BC051693 BC069377 AAH69377 BC069433 AAH69433 BC098396 AAH98396 BC113531 AAI13532 BC117260 AAI17261 BC143831 AAI43832 BC143832 AAI43833 BC144601 CR536495 CAG38734 CR541692 CAG46493 DB445256 DC347823 HQ258749 ADR83500 L06895 AAA36194 NM_001202513 NP_001189442 NM_001202514 NP_001189443 NM_002357 NP_002348
|
| Function |
Transcriptional repressor. MAD binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. MAD thus antagonizes MYC transcriptional activity by competing for MAX.
|
| Subcellular Location |
Nucleus.
|
