Gene Symbol | GAA |
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Entrez Gene | 2548 |
Alt Symbol | LYAG |
Species | Human |
Gene Type | protein-coding |
Description | glucosidase, alpha; acid |
Other Description | acid maltase|aglucosidase alfa|lysosomal alpha-glucosidase |
Swissprots | Q14351 P10253 Q16302 Q09GN4 Q8IWE7 |
Accessions | CAC12967 EAW89581 EAW89582 EAW89583 P10253 AK299462 BAH13042 AW515241 BC015908 BC040431 AAH40431 BC065262 BQ711289 DQ907243 ABI53718 M34424 AAA52506 S76893 AAB33842 Y00839 CAA68763 XM_005257193 XP_005257250 XM_005257194 XP_005257251 NM_000152 NP_000143 NM_001079803 NP_001073271 NM_001079804 NP_001073272 |
Function | Essential for the degradation of glygogen to glucose in lysosomes. |
Subcellular Location | Lysosome {ECO:0000269|PubMed:17897319}. Lysosome membrane {ECO:0000269|PubMed:17897319}. |
Top Pathways | Lysosome, Galactose metabolism, Starch and sucrose metabolism |
LYAG CRISPR/Cas9 KO Plasmid (h) - sc-402385 from Santa Cruz Biotechnology
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LYAG HDR Plasmid (h) - sc-402385-HDR from Santa Cruz Biotechnology
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LYAG Double Nickase Plasmid (h) - sc-402385-NIC from Santa Cruz Biotechnology
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LYAG Double Nickase Plasmid (h2) - sc-402385-NIC-2 from Santa Cruz Biotechnology
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LYAG CRISPR Activation Plasmid (h) - sc-402385-ACT from Santa Cruz Biotechnology
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LYAG CRISPR Activation Plasmid (h2) - sc-402385-ACT-2 from Santa Cruz Biotechnology
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LYAG Lentiviral Activation Particles (h) - sc-402385-LAC from Santa Cruz Biotechnology
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LYAG Lentiviral Activation Particles (h2) - sc-402385-LAC-2 from Santa Cruz Biotechnology
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LYAG siRNA (h) - sc-60974 from Santa Cruz Biotechnology
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LYAG shRNA Plasmid (h) - sc-60974-SH from Santa Cruz Biotechnology
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LYAG shRNA (h) Lentiviral Particles - sc-60974-V from Santa Cruz Biotechnology
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LYAG/GAA RNAi - H00002548-R01 from Novus Biologicals
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LYAG/GAA RNAi - H00002548-R02 from Novus Biologicals
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LYAG/GAA RNAi - H00002548-R03 from Novus Biologicals
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MISSION® esiRNA - EHU070081 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1895 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1895 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04107 from Sigma-Aldrich
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GAA siRNA (Human) - CRH1687 from Cohesion Biosciences
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GAA - MBS8217186 from MyBioSource
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Human GAA siRNA - orb262189 from Biorbyt
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GAA shRNA Plasmid (Human) - CHH1687 from Cohesion Biosciences
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