Gene Symbol | APOBEC2 |
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Entrez Gene | 10930 |
Alt Symbol | ARCD1, ARP1 |
Species | Human |
Gene Type | protein-coding |
Description | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 |
Other Description | apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2|probable C->U-editing enzyme APOBEC-2 |
Swissprots | Q5TGU5 Q53F28 Q9Y235 B2R899 Q5TGU6 |
Accessions | EAX04009 Q9Y235 AF086496 AF161698 AAD45360 AI096570 AK223461 BAD97181 AK300689 BAG62372 AK308197 AK310006 AK313288 BAG36096 BC047767 AAH47767 BC069688 AAH69688 BC069764 AAH69764 BI438931 CB051273 NM_006789 NP_006780 |
Function | Probable C to U editing enzyme whose physiological substrate is not yet known. Does not display detectable apoB mRNA editing. Has a low intrinsic cytidine deaminase activity. May play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation. {ECO:0000269|PubMed:21496894}. |
Tissue Specificity | Expressed exclusively in heart and skeletal muscle. |
APOBEC2 CRISPR/Cas9 KO Plasmid (h) - sc-410563 from Santa Cruz Biotechnology
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APOBEC2 HDR Plasmid (h) - sc-410563-HDR from Santa Cruz Biotechnology
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APOBEC2 Double Nickase Plasmid (h) - sc-410563-NIC from Santa Cruz Biotechnology
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APOBEC2 Double Nickase Plasmid (h2) - sc-410563-NIC-2 from Santa Cruz Biotechnology
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APOBEC2 CRISPR Activation Plasmid (h) - sc-410563-ACT from Santa Cruz Biotechnology
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APOBEC2 CRISPR Activation Plasmid (h2) - sc-410563-ACT-2 from Santa Cruz Biotechnology
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APOBEC2 Lentiviral Activation Particles (h) - sc-410563-LAC from Santa Cruz Biotechnology
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APOBEC2 Lentiviral Activation Particles (h2) - sc-410563-LAC-2 from Santa Cruz Biotechnology
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APOBEC2 siRNA (h) - sc-95404 from Santa Cruz Biotechnology
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APOBEC2 shRNA Plasmid (h) - sc-95404-SH from Santa Cruz Biotechnology
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APOBEC2 shRNA (h) Lentiviral Particles - sc-95404-V from Santa Cruz Biotechnology
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APOBEC2 RNAi - H00010930-R01 from Novus Biologicals
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MISSION® esiRNA - EHU007461 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3333 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3333 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03314 from Sigma-Aldrich
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APOBEC2 siRNA (Human) - CRH7456 from Cohesion Biosciences
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APOBEC2 - MBS8214244 from MyBioSource
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shRNA set against Human APOBEC2 (NM_006789.3) - SHH238406 from Creative biogene
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Human APOBEC2 siRNA - orb267958 from Biorbyt
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APOBEC2 shRNA Plasmid (Human) - CHH7456 from Cohesion Biosciences
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APOBEC2 miRNA 3'UTR clone - MiUTR4H-TG00413 from Creative biogene
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