| Gene Symbol |
ADGRG6
|
| Entrez Gene |
57211
|
| Alt Symbol |
APG1, DREG, GPR126, PS1TP2, VIGR
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
adhesion G protein-coupled receptor G6
|
| Other Description |
G protein-coupled receptor 126|G-protein coupled receptor 126|HBV PreS1-transactivated protein 2|developmentally regulated G-protein-coupled receptor|vascular inducible G protein-coupled receptor|vascular-inducible G protein-coupled receptor
|
| Swissprots |
Q6F3F8 Q86SQ4 Q96JW0 Q8NC14 Q5TGN7 Q6F3F5 Q6DHZ4 Q6MZU7 Q6F3F6 Q6F3F7 Q8IXA4
|
| Accessions |
EAW47875 EAW47876 EAW47877 EAW47878 EAW47879 EAW47880 EAW47881 Q86SQ4 AB183546 BAD27571 AB183547 BAD27572 AB183548 BAD27573 AB183549 BAD27574 AF216967 AAO13250 AK027843 BAB55406 AK075087 BAC11393 AK092519 AK122617 AK299785 BAG61666 AK307543 AL080079 AY181244 AAO27356 AY426673 AAR88427 BC036008 BC075798 AAH75798 BX640873 CAE45930 BX640971 CAE45986 BX648315 XM_005267061 XP_005267118 XM_006715516 XP_006715579 XM_006715517 XP_006715580 XM_006715518 XP_006715581 XM_011535964 XP_011534266 NM_001032394 NP_001027566 NM_001032395 NP_001027567 NM_020455 NP_065188 NM_198569 NP_940971
|
| Function |
Orphan receptor. May be required for normal differentiation of promyelinating Schwann cells and for normal myelination of axons. Signals probably through G-proteins to transiently elevate cAMP levels (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:15189448, ECO:0000269|PubMed:15225624}; Multi-pass membrane protein {ECO:0000269|PubMed:15189448, ECO:0000269|PubMed:15225624}. Note=Detected on the cell surface of activated but not resting umbilical vein.
|
| Tissue Specificity |
Expressed in placenta and to a lower extent in pancreas and liver. Detected in aortic endothelial cells but not in skin microvascular endothelial cells. {ECO:0000269|PubMed:15225624}.
|