Gene Symbol | CCL11 |
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Entrez Gene | 6356 |
Alt Symbol | SCYA11 |
Species | Human |
Gene Type | protein-coding |
Description | chemokine (C-C motif) ligand 11 |
Other Description | eosinophil chemotactic protein|eotaxin|eotaxin-1|small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin) |
Swissprots | Q92491 P50877 Q92490 P51671 |
Accessions | AAC50369 AAC51297 ABK41951 CAB07027 EAW80209 P51671 AI446061 BC017850 AAH17850 BF197516 CR457421 CAG33702 DQ891969 ABM82895 DQ895158 ABM86084 U46573 AAA98957 Z69291 CAA93258 Z75668 CAA99997 Z75669 CAA99998 NM_002986 NP_002977 |
Function | In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3. |
Subcellular Location | Secreted. |
Top Pathways | Cytokine-cytokine receptor interaction, Asthma, Chemokine signaling pathway |
eotaxin CRISPR/Cas9 KO Plasmid (h) - sc-403103 from Santa Cruz Biotechnology
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eotaxin HDR Plasmid (h) - sc-403103-HDR from Santa Cruz Biotechnology
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eotaxin Double Nickase Plasmid (h) - sc-403103-NIC from Santa Cruz Biotechnology
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eotaxin Double Nickase Plasmid (h2) - sc-403103-NIC-2 from Santa Cruz Biotechnology
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eotaxin CRISPR Activation Plasmid (h) - sc-403103-ACT from Santa Cruz Biotechnology
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eotaxin CRISPR Activation Plasmid (h2) - sc-403103-ACT-2 from Santa Cruz Biotechnology
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eotaxin Lentiviral Activation Particles (h) - sc-403103-LAC from Santa Cruz Biotechnology
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eotaxin Lentiviral Activation Particles (h2) - sc-403103-LAC-2 from Santa Cruz Biotechnology
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eotaxin siRNA (h) - sc-43753 from Santa Cruz Biotechnology
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eotaxin shRNA Plasmid (h) - sc-43753-SH from Santa Cruz Biotechnology
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eotaxin shRNA (h) Lentiviral Particles - sc-43753-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU151041 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5597 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5597 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04218 from Sigma-Aldrich
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CCL11 siRNA (Human) - CRH4289 from Cohesion Biosciences
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CCL11/Eotaxin RNAi - H00006356-R01 from Novus Biologicals
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CCL11 - MBS8238622 from MyBioSource
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shRNA set against Human CCL11 (NM_002986.2) - SHH257485 from Creative biogene
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shRNA set against Human CCL11(NM_002986.2) - SHG134467 from Creative biogene
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Human CCL11 siRNA - orb264791 from Biorbyt
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CCL11 shRNA Plasmid (Human) - CHH4289 from Cohesion Biosciences
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CCL11 miRNA 3'UTR clone - MiUTR1H-01790 from Creative biogene
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