Gene Symbol | MCHR2 |
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Entrez Gene | 84539 |
Alt Symbol | GPR145, GPRv17, MCH-2R, MCH-R2, MCH2, MCH2R, MCHR-2, SLT |
Species | Human |
Gene Type | protein-coding |
Description | melanin-concentrating hormone receptor 2 |
Other Description | G protein-coupled receptor 145|G protein-coupled receptor slt|G-protein coupled receptor 145|MCH receptor 2|melanin-concentrating hormone 2 |
Swissprots | B3KVW4 Q5VTV7 Q9BXA8 Q6Q377 E1P5D7 Q969V1 |
Accessions | EAW48459 EAW48460 Q969V1 AB058849 BAB87842 AB060151 BAB55677 AF347063 AAK32193 AF399937 AAL05528 AK123634 BAG53926 AY029596 AAK38157 AY562946 AAS72374 BC038441 BC095515 AAH95515 NM_001040179 NP_001035269 NM_032503 NP_115892 |
Function | Receptor for melanin-concentrating hormone, coupled to G proteins that activate phosphoinositide hydrolysis. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Specifically expressed in the brain, with highest levels in cerebral cortex, hippocampus and amygdala. No expression detected in the cerebellum, thalamus or hypothalamus. |
Top Pathways | Neuroactive ligand-receptor interaction |
MCH-2R CRISPR/Cas9 KO Plasmid (h) - sc-413661 from Santa Cruz Biotechnology
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MCH-2R HDR Plasmid (h) - sc-413661-HDR from Santa Cruz Biotechnology
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MCH-2R Double Nickase Plasmid (h) - sc-413661-NIC from Santa Cruz Biotechnology
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MCH-2R Double Nickase Plasmid (h2) - sc-413661-NIC-2 from Santa Cruz Biotechnology
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MCH-2R CRISPR Activation Plasmid (h) - sc-413661-ACT from Santa Cruz Biotechnology
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MCH-2R CRISPR Activation Plasmid (h2) - sc-413661-ACT-2 from Santa Cruz Biotechnology
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MCH-2R Lentiviral Activation Particles (h) - sc-413661-LAC from Santa Cruz Biotechnology
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MCH-2R Lentiviral Activation Particles (h2) - sc-413661-LAC-2 from Santa Cruz Biotechnology
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MCH-2R siRNA (h) - sc-42019 from Santa Cruz Biotechnology
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MCH-2R shRNA Plasmid (h) - sc-42019-SH from Santa Cruz Biotechnology
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MCH-2R shRNA (h) Lentiviral Particles - sc-42019-V from Santa Cruz Biotechnology
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MCHR2 RNAi - H00084539-R02 from Novus Biologicals
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MISSION® esiRNA - EHU012701 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN13114 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13114 from Sigma-Aldrich
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MCHR2 siRNA (Human) - CRJ3515 from Cohesion Biosciences
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shRNA set against Human MCHR2 (NM_032503.2) - SHH339247 from Creative biogene
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shRNA set against Human MCHR2(NM_001040179.1) - SHH181127 from Creative biogene
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Human MCHR2 siRNA - orb274016 from Biorbyt
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MCHR2 shRNA Plasmid (Human) - CHJ3515 from Cohesion Biosciences
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MCHR2 miRNA 3'UTR clone - MiUTR1H-06162 from Creative biogene
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MCHR2 miRNA 3'UTR clone - MiUTR3H-08225 from Creative biogene
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