Gene Symbol | Hpd |
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Entrez Gene | 29531 |
Alt Symbol | - |
Species | Rat |
Gene Type | protein-coding |
Description | 4-hydroxyphenylpyruvate dioxygenase |
Other Description | 4-hydroxyphenylpyruvic acid dioxygenase|4-hydroxyphenylpyruvic acid oxidase|4HPPD|HPPDase|f Alloantigen|f protein |
Swissprots | O88655 P32755 |
Accessions | EDM13651 P32755 AF082834 AAC32387 BC081819 AAH81819 FQ209393 FQ209489 FQ210905 FQ218378 FQ218745 FQ219696 M18405 AAA40740 NM_017233 NP_058929 |
Function | Key enzyme in the degradation of tyrosine. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:12867153}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:12867153}; Peripheral membrane protein {ECO:0000269|PubMed:12867153}. Golgi apparatus membrane {ECO:0000269|PubMed:12867153}; Peripheral membrane protein {ECO:0000269|PubMed:12867153}. |
Top Pathways | Ubiquinone and other terpenoid-quinone biosynthesis, Phenylalanine metabolism, Tyrosine metabolism |
CompoZr® Knockout ZFN Kit - CKOZFN55166 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND55166 from Sigma-Aldrich
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HPD siRNA (Rat) - CRR1218 from Cohesion Biosciences
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HPD - MBS8230699 from MyBioSource
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shRNA set against Rat HPD (NM_017233.1) - SHH314577 from Creative biogene
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shRNA set against Rat Hpd(NM_017233.1) - SHH130007 from Creative biogene
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HPD shRNA Plasmid (Rat) - CHR1218 from Cohesion Biosciences
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HPD miRNA 3'UTR clone - MiUTR1R-02488 from Creative biogene
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