Gene Symbol |
PAFAH2
|
Entrez Gene |
5051
|
Alt Symbol |
HSD-PLA2
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
platelet-activating factor acetylhydrolase 2, 40kDa
|
Other Description |
SD-PLA2|platelet-activating factor acetylhydrolase 2, cytoplasmic|serine-dependent phospholipase A2
|
Swissprots |
O15458 D3DPK1 Q99487 Q5SY02
|
Accessions |
EAX07852 EAX07853 Q99487 AK313815 BAG36551 BC001158 AAH01158 BU630496 D87845 BAA13468 DQ892796 ABM83722 DQ896043 ABM87042 U89386 AAC39707 XM_006710669 XP_006710732 XM_006710670 XP_006710733 XM_011541528 XP_011539830 XM_011541529 XP_011539831 NM_000437 NP_000428
|
Function |
Has a marked selectivity for phospholipids with short acyl chains at the sn-2 position. May share a common physiologic function with the plasma-type enzyme.
|
Subcellular Location |
Cytoplasm.
|
Tissue Specificity |
Broadly expressed in different tissues, but high in B- and T-lymphocytes. In brain, expression is restricted to amygdala and frontal cortex.
|
Top Pathways |
Ether lipid metabolism
|