| Gene Symbol | FCER1G |
|---|---|
| Entrez Gene | 2207 |
| Alt Symbol | FCRG |
| Species | Human |
| Gene Type | protein-coding |
| Description | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide |
| Other Description | Fc receptor gamma-chain|fc-epsilon RI-gamma|fcRgamma|fceRI gamma|high affinity immunoglobulin epsilon receptor subunit gamma|immunoglobulin E receptor, high affinity, gamma chain |
| Swissprots | P30273 Q5VTW4 |
| Accessions | CBK51078 CCF76977 EAW52623 EAW52624 P30273 AK307102 BC033872 AAH33872 DQ890782 ABM81708 EU176502 ABW03303 M33195 AAA35828 NM_004106 NP_004097 |
| Function | Associates with a variety of FcR alpha chains to form a functional signaling complex. Regulates several aspects of the immune response. The gamma subunit has a critical role in allowing the IgE Fc receptor to reach the cell surface. Also involved in collagen-mediated platelet activation and in neutrophil activation mediated by integrin. {ECO:0000269|PubMed:8611682}. |
| Subcellular Location | Cell membrane {ECO:0000269|PubMed:8611682}; Single-pass type I membrane protein {ECO:0000269|PubMed:8611682}. |
| Top Pathways | Natural killer cell mediated cytotoxicity, Fc epsilon RI signaling pathway, Asthma, Tuberculosis, Sphingolipid signaling pathway |