Gene Symbol | COX1 |
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Entrez Gene | 4512 |
Alt Symbol | COI, MTCO1 |
Species | Human |
Gene Type | protein-coding |
Description | cytochrome c oxidase subunit I |
Other Description | - |
Swissprots | Q34770 P00395 |
Accessions | AAB58945 YP_003024028 |
Function | Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. |
Subcellular Location | Mitochondrion inner membrane; Multi-pass membrane protein. |
Top Pathways | Alzheimer's disease, Huntington's disease, Cardiac muscle contraction, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation |
COX1 (C-20) - sc-23982 from Santa Cruz Biotechnology
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COX1 (T-20) - sc-48143 from Santa Cruz Biotechnology
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Anti-MTCO1 antibody - ab45918 from Abcam
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Anti-MTCO1 antibody - ab90668 from Abcam
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Anti-MT-CO1 / COX1 Antibody (aa501-514) - LS-C343872 from LifeSpan Bioscience
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Anti-MT-CO1 / COX1 Antibody (aa501-514) - LS-C343871 from LifeSpan Bioscience
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Anti-MT-CO1 / COX1 Antibody (N-Terminus) - LS-C128363 from LifeSpan Bioscience
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Anti-MT-CO1 / COX1 Antibody (N-Terminus, Magnetic beads) - LS-C172111 from LifeSpan Bioscience
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Anti-MT-CO1 / COX1 Antibody - LS-C194983 from LifeSpan Bioscience
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Anti-MT-CO1 / COX1 Antibody (N-Terminus, Sepharose) - LS-C172112 from LifeSpan Bioscience
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Anti-MT-CO1 / COX1 Antibody (aa202-232, AP) - LS-C234138 from LifeSpan Bioscience
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Anti-MT-CO1 / COX1 Antibody (aa202-232, Biotin) - LS-C234139 from LifeSpan Bioscience
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Anti-MT-CO1 / COX1 Antibody (aa202-232, APC) - LS-C234140 from LifeSpan Bioscience
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Anti-MT-CO1 / COX1 Antibody (aa202-232, PE) - LS-C234145 from LifeSpan Bioscience
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Anti-MT-CO1 / COX1 Antibody (aa202-232, FITC) - LS-C234141 from LifeSpan Bioscience
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Anti-MT-CO1 / COX1 Antibody (aa202-232, Azide-free, HRP) - LS-C249734 from LifeSpan Bioscience
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Anti-MT-CO1 / COX1 Antibody (aa202-232) - LS-C329414 from LifeSpan Bioscience
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Anti-MT-CO1 / COX1 Antibody (N-Terminus) - LS-C172110 from LifeSpan Bioscience
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Anti-MT-CO1 / COX1 Antibody (aa195-224) - LS-C166973 from LifeSpan Bioscience
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MTCO1 Antibody - NBP2-29949 from Novus Biologicals
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COX1/MTCO1 Polyclonal Antibody - bs-3953R from Bioss
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ANTI-COXI (CENTER) antibody produced in rabbit - SAB1301619 from Sigma-Aldrich
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COXI-Antibody-Center - AP9684c from Abgent, a WuXi AppTec company
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COX1 Antibody - middle region (OAAB06281) - OAAB06281 from Aviva Systems Biology
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MT-CO1 antibody - orb18171 from Biorbyt
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