| Gene Symbol |
SEPHS1
|
| Entrez Gene |
22929
|
| Alt Symbol |
SELD, SPS, SPS1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
selenophosphate synthetase 1
|
| Other Description |
selenide, water dikinase 1|selenium donor protein 1|selenophosphate synthase 1|selenophosphate synthetase 1 +E9|selenophosphate synthetase 1 +E9a|selenophosphate synthetase 1 delta E2|selenophosphate synthetase 1 delta E8|selenophosphate synthetase 1 major
|
| Swissprots |
Q9BVT4 Q5T5U8 D6PSQ9 D3DRS9 B4DWK0 P49903 Q5T5U9
|
| Accessions |
CBX51405 EAW86289 EAW86290 EAW86291 EAW86292 EAW86293 P49903 AK125066 AK297129 BAG59633 AK301568 BAG63062 AK309829 AL557595 AL579174 BC000941 AAH00941 BC063816 AAH63816 BC064610 CT000832 DQ894137 ABM85063 GU954545 ADF78120 GU954546 ADF78121 GU954547 ADF78122 GU954548 ADF78123 GU954549 ADF78124 U34044 AAA87567 XM_006717433 XP_006717496 NM_001195602 NP_001182531 NM_001195604 NP_001182533 NM_012247 NP_036379
|
| Function |
Synthesizes selenophosphate from selenide and ATP. {ECO:0000269|PubMed:7665581}.
|
| Subcellular Location |
Isoform 3: Cytoplasm.
|
| Tissue Specificity |
Isoform 1 and isoform 2 are gradually expressed during the cell cycle until G2/M phase and then decreased. Isoform 3 is gradually expressed during the cell cycle until S phase and then decreased. {ECO:0000269|PubMed:20471958}.
|
| Top Pathways |
Selenocompound metabolism
|
![Western Blot: SEPHS1 Overexpression Lysate (Adult Normal) [NBL1-15814] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SEPHS1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/7128_SEPHS1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-15814-img0002.jpg)