Gene Symbol | LHFPL5 |
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Entrez Gene | 222662 |
Alt Symbol | DFNB67, TMHS, dJ510O8.8 |
Species | Human |
Gene Type | protein-coding |
Description | lipoma HMGIC fusion partner-like 5 |
Other Description | LHFP-like protein 5|lipoma HMGIC fusion partner-like 5 protein|tetraspan membrane protein of hair cell stereocilia |
Swissprots | B3KX66 Q8TAF8 |
Accessions | EAX03852 Q8TAF8 AK126841 BAG54378 BC028630 AAH28630 DQ891208 ABM82134 DQ894391 ABM85317 XM_011514403 XP_011512705 NM_182548 NP_872354 |
Function | In the inner ear, may be a component of the hair cell's mechanotransduction machinery that functionally couples PCDH15 to the transduction channel. Regulates transducer channel conductance and is required for fast channel adaptation (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Efficient localization to the plasma membrane requires the presence of PCDH15. {ECO:0000250}. |
LHFPL5 CRISPR/Cas9 KO Plasmid (h) - sc-408349 from Santa Cruz Biotechnology
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LHFPL5 HDR Plasmid (h) - sc-408349-HDR from Santa Cruz Biotechnology
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LHFPL5 Double Nickase Plasmid (h) - sc-408349-NIC from Santa Cruz Biotechnology
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LHFPL5 Double Nickase Plasmid (h2) - sc-408349-NIC-2 from Santa Cruz Biotechnology
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LHFPL5 CRISPR Activation Plasmid (h) - sc-408349-ACT from Santa Cruz Biotechnology
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LHFPL5 CRISPR Activation Plasmid (h2) - sc-408349-ACT-2 from Santa Cruz Biotechnology
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LHFPL5 Lentiviral Activation Particles (h) - sc-408349-LAC from Santa Cruz Biotechnology
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LHFPL5 Lentiviral Activation Particles (h2) - sc-408349-LAC-2 from Santa Cruz Biotechnology
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LHFPL5 siRNA (h) - sc-95425 from Santa Cruz Biotechnology
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LHFPL5 shRNA Plasmid (h) - sc-95425-SH from Santa Cruz Biotechnology
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LHFPL5 shRNA (h) Lentiviral Particles - sc-95425-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN11690 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11690 from Sigma-Aldrich
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LHFPL5 siRNA (Human) - CRJ6577 from Cohesion Biosciences
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shRNA set against Human LHFPL5 (NM_182548.3) - SHH330071 from Creative biogene
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shRNA set against Human LHFPL5(NM_182548.3) - SHH148421 from Creative biogene
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Human LHFPL5 siRNA - orb277078 from Biorbyt
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LHFPL5 shRNA Plasmid (Human) - CHJ6577 from Cohesion Biosciences
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LHFPL5 miRNA 3'UTR clone - MiUTR1H-05659 from Creative biogene
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