Gene Symbol | Ddc |
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Entrez Gene | 13195 |
Alt Symbol | Aadc |
Species | Mouse |
Gene Type | protein-coding |
Description | dopa decarboxylase |
Other Description | aromatic-L-amino-acid decarboxylase |
Swissprots | O88533 |
Accessions | EDL40647 O88533 AA986109 AF012881 AAB84011 AF012882 AAB84012 AF071068 AAC25566 AK011834 AK050963 AK149141 BAE28750 AK160769 BAE35999 BC060989 BC089594 BC152724 AAI52725 BY129740 XM_006514486 XP_006514549 XM_006514487 XP_006514550 XM_006514488 XP_006514551 XM_006514489 XP_006514552 NM_001190448 NP_001177377 NM_016672 NP_057881 |
Function | Catalyzes the decarboxylation of L-3,4- dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. |
Top Pathways | Dopaminergic synapse, Alcoholism, Cocaine addiction, Amphetamine addiction, Phenylalanine metabolism |
DDC CRISPR/Cas9 KO Plasmid (m) - sc-419967 from Santa Cruz Biotechnology
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DDC HDR Plasmid (m) - sc-419967-HDR from Santa Cruz Biotechnology
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DDC Double Nickase Plasmid (m) - sc-419967-NIC from Santa Cruz Biotechnology
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DDC Double Nickase Plasmid (m2) - sc-419967-NIC-2 from Santa Cruz Biotechnology
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DDC CRISPR Activation Plasmid (m) - sc-419967-ACT from Santa Cruz Biotechnology
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DDC CRISPR Activation Plasmid (m2) - sc-419967-ACT-2 from Santa Cruz Biotechnology
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DDC Lentiviral Activation Particles (m) - sc-419967-LAC from Santa Cruz Biotechnology
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DDC Lentiviral Activation Particles (m2) - sc-419967-LAC-2 from Santa Cruz Biotechnology
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DDC siRNA (m) - sc-60516 from Santa Cruz Biotechnology
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DDC shRNA Plasmid (m) - sc-60516-SH from Santa Cruz Biotechnology
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DDC shRNA (m) Lentiviral Particles - sc-60516-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU062541 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN29786 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND29786 from Sigma-Aldrich
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DDC siRNA (Mouse) - CRM0993 from Cohesion Biosciences
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DDC - MBS8240402 from MyBioSource
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shRNA set against Mouse DDC (NM_016672.4) - SHH275593 from Creative biogene
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Mouse DDC siRNA - orb280469 from Biorbyt
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DDC shRNA Plasmid (Mouse) - CHM0993 from Cohesion Biosciences
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