Gene Symbol | RIT2 |
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Entrez Gene | 6014 |
Alt Symbol | RIBA, RIN, ROC2 |
Species | Human |
Gene Type | protein-coding |
Description | Ras-like without CAAX 2 |
Other Description | GTP-binding protein Rit2|GTP-binding protein Roc2|Ric-like, expressed in neurons|ras-like protein expressed in neurons|ras-like without CAAX protein 2 |
Swissprots | O15295 Q8WVF6 B2R9L1 Q99578 Q8TD69 Q92964 |
Accessions | EAX01432 Q99578 AF493922 AAM12636 AK313823 BAG36558 AY563951 AAS75332 BC018060 AAH18060 BG188523 JF432616 ADZ15833 U71204 AAB42214 U78164 AAB64245 U78166 AAB64247 Y07565 CAA68850 NM_001272077 NP_001259006 NM_002930 NP_002921 |
Function | Binds and exchanges GTP and GDP. {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:16122393}. Cell membrane {ECO:0000269|PubMed:16122393}. Note=Colocalizes with PLXNB3 at the plasma membrane. |
Tissue Specificity | Neuron-specific. |
Rit2 CRISPR/Cas9 KO Plasmid (h) - sc-405599 from Santa Cruz Biotechnology
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Rit2 HDR Plasmid (h) - sc-405599-HDR from Santa Cruz Biotechnology
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Rit2 Double Nickase Plasmid (h) - sc-405599-NIC from Santa Cruz Biotechnology
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Rit2 Double Nickase Plasmid (h2) - sc-405599-NIC-2 from Santa Cruz Biotechnology
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Rit2 CRISPR Activation Plasmid (h) - sc-405599-ACT from Santa Cruz Biotechnology
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Rit2 CRISPR Activation Plasmid (h2) - sc-405599-ACT-2 from Santa Cruz Biotechnology
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Rit2 Lentiviral Activation Particles (h) - sc-405599-LAC from Santa Cruz Biotechnology
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Rit2 Lentiviral Activation Particles (h2) - sc-405599-LAC-2 from Santa Cruz Biotechnology
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Rit2 siRNA (h) - sc-62950 from Santa Cruz Biotechnology
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Rit2 shRNA Plasmid (h) - sc-62950-SH from Santa Cruz Biotechnology
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Rit2 shRNA (h) Lentiviral Particles - sc-62950-V from Santa Cruz Biotechnology
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Rit2 RNAi - H00006014-R01 from Novus Biologicals
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MISSION® esiRNA - EHU068901 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN18303 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18303 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01941 from Sigma-Aldrich
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RIT2 siRNA (Human) - CRH4080 from Cohesion Biosciences
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RIT2 - MBS8208517 from MyBioSource
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shRNA set against Human RIT2 (NM_002930.2) - SHH396085 from Creative biogene
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shRNA set against Human RIT2(NM_002930.2) - SHR183030 from Creative biogene
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Human RIT2 siRNA - orb264582 from Biorbyt
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RIT2 shRNA Plasmid (Human) - CHH4080 from Cohesion Biosciences
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RIT2 miRNA 3'UTR clone - MiUTR1H-08837 from Creative biogene
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