Gene Symbol | DDX6 |
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Entrez Gene | 1656 |
Alt Symbol | HLR2, P54, RCK |
Species | Human |
Gene Type | protein-coding |
Description | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
Other Description | ATP-dependent RNA helicase p54|DEAD (Asp-Glu-Ala-Asp) box polypeptide 6|DEAD box protein 6|DEAD box-6|DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 6 (RNA helicase, 54kD)|oncogene RCK|probable ATP-dependent RNA helicase DDX6 |
Swissprots | P26196 Q5D048 |
Accessions | CBM42913 CBV35646 EAW67412 EAW67413 P26196 AI265778 AK021715 AK093657 AK313244 BAG36055 BC026228 BC039826 AAH39826 BC065007 AAH65007 BF810127 D17532 BAA04482 DA993470 HQ448157 ADQ32638 Z11685 XM_005271417 XP_005271474 XM_011542644 XP_011540946 XM_011542645 XP_011540947 NM_001257191 NP_001244120 NM_004397 NP_004388 |
Function | In the process of mRNA degradation, may play a role in mRNA decapping. |
Subcellular Location | Cytoplasm, P-body {ECO:0000269|PubMed:16364915, ECO:0000269|PubMed:16699599, ECO:0000269|PubMed:20616046, ECO:0000269|PubMed:22915799}. |
Tissue Specificity | Abundantly expressed in most tissues. |
Top Pathways | RNA degradation |
RCK CRISPR/Cas9 KO Plasmid (h) - sc-417748 from Santa Cruz Biotechnology
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RCK HDR Plasmid (h) - sc-417748-HDR from Santa Cruz Biotechnology
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RCK Double Nickase Plasmid (h) - sc-417748-NIC from Santa Cruz Biotechnology
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RCK Double Nickase Plasmid (h2) - sc-417748-NIC-2 from Santa Cruz Biotechnology
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RCK CRISPR Activation Plasmid (h) - sc-417748-ACT from Santa Cruz Biotechnology
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RCK CRISPR Activation Plasmid (h2) - sc-417748-ACT-2 from Santa Cruz Biotechnology
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RCK Lentiviral Activation Particles (h) - sc-417748-LAC from Santa Cruz Biotechnology
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RCK Lentiviral Activation Particles (h2) - sc-417748-LAC-2 from Santa Cruz Biotechnology
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RCK siRNA (h) - sc-72246 from Santa Cruz Biotechnology
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RCK shRNA Plasmid (h) - sc-72246-SH from Santa Cruz Biotechnology
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RCK shRNA (h) Lentiviral Particles - sc-72246-V from Santa Cruz Biotechnology
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DDX6 RNAi - H00001656-R01V from Novus Biologicals
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MISSION® esiRNA - EHU107381 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7072 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7072 from Sigma-Aldrich
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DDX6 siRNA (Human) - CRH1168 from Cohesion Biosciences
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DDX6 RNAi - H00001656-R02 from Novus Biologicals
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DDX6 - MBS8215338 from MyBioSource
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shRNA set against Human DDX6(NM_004397.4) - SHG227491 from Creative biogene
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Human DDX6 siRNA - orb261670 from Biorbyt
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DDX6 shRNA Plasmid (Human) - CHH1168 from Cohesion Biosciences
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DDX6 miRNA 3'UTR clone - MiUTR1H-02744 from Creative biogene
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