| Gene Symbol |
MTERF1
|
| Entrez Gene |
7978
|
| Alt Symbol |
MTERF
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
mitochondrial transcription termination factor 1
|
| Other Description |
transcription termination factor 1, mitochondrial|transcription termination factor, mitochondrial
|
| Swissprots |
Q53H51 Q99551 Q32NF8 Q9BVR7 A4D1E3
|
| Accessions |
AAB83941 CAD35015 EAL24159 EAW76869 Q99551 AK222730 BAD96450 AK298469 BAG60681 AK313641 BAG36399 AL832861 BC000965 AAH00965 BC108648 AAI08649 BC130389 AAI30390 BC130391 AAI30392 BU740531 DQ894141 ABM85067 HQ258403 ADR83157 Y09615 CAA70830 XM_005250593 XP_005250650 XM_006716126 XP_006716189 NM_001301134 NP_001288063 NM_001301135 NP_001288064 NM_006980 NP_008911
|
| Function |
Transcription termination factor. Binds to a 28 bp region within the tRNA(Leu(uur)) gene at a position immediately adjacent to and downstream of the 16S rRNA gene; this region comprises a tridecamer sequence critical for directing accurate termination. Binds DNA along the major grove and promotes DNA bending and partial unwinding. Promotes base flipping. Transcription termination activity appears to be polarized with highest specificity for transcripts initiated on the light strand. {ECO:0000269|PubMed:20550934}.
|
| Subcellular Location |
Mitochondrion.
|