Gene Symbol | TRIB1 |
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Entrez Gene | 10221 |
Alt Symbol | C8FW, GIG-2, GIG2, SKIP1, TRB-1, TRB1 |
Species | Human |
Gene Type | protein-coding |
Description | tribbles pseudokinase 1 |
Other Description | G-protein-coupled receptor induced protein|G-protein-coupled receptor-induced gene 2 protein|G-protein-coupled receptor-induced protein 2|phosphoprotein regulated by mitogenic pathways|tribbles homolog 1|tribbles-like protein 1 |
Swissprots | B4DMM6 C5HU08 Q96RU8 O15180 Q9H2Y8 |
Accessions | ACS13752 CAS91544 CCD74463 EAW92085 Q96RU8 AF205437 AAG35663 AF250310 AAK58174 AJ000480 CAA04119 AK001319 AK022787 AK297539 BAG59938 AK307561 AL832388 CAI46181 BC012441 BC063292 AAH63292 DA686993 XR_428373 NM_001282985 NP_001269914 NM_025195 NP_079471 |
Function | Interacts with MAPK kinases and regulates activation of MAP kinases. May not display kinase activity. {ECO:0000269|PubMed:15299019, ECO:0000303|PubMed:15299019}. |
Tissue Specificity | Expressed in most human tissues with the highest levels in skeletal muscle, thyroid gland, pancreas, peripheral blood leukocytes, and bone marrow. {ECO:0000269|PubMed:15299019}. |
TRB-1 CRISPR/Cas9 KO Plasmid (h) - sc-405781 from Santa Cruz Biotechnology
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TRB-1 HDR Plasmid (h) - sc-405781-HDR from Santa Cruz Biotechnology
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TRB-1 Double Nickase Plasmid (h) - sc-405781-NIC from Santa Cruz Biotechnology
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TRB-1 Double Nickase Plasmid (h2) - sc-405781-NIC-2 from Santa Cruz Biotechnology
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TRB-1 CRISPR Activation Plasmid (h) - sc-405781-ACT from Santa Cruz Biotechnology
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TRB-1 CRISPR Activation Plasmid (h2) - sc-405781-ACT-2 from Santa Cruz Biotechnology
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TRB-1 Lentiviral Activation Particles (h) - sc-405781-LAC from Santa Cruz Biotechnology
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TRB-1 Lentiviral Activation Particles (h2) - sc-405781-LAC-2 from Santa Cruz Biotechnology
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TRB-1 siRNA (h) - sc-77704 from Santa Cruz Biotechnology
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TRB-1 shRNA Plasmid (h) - sc-77704-SH from Santa Cruz Biotechnology
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TRB-1 shRNA (h) Lentiviral Particles - sc-77704-V from Santa Cruz Biotechnology
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TRIB1 RNAi - H00010221-R02 from Novus Biologicals
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MISSION® esiRNA - EHU016141 from Sigma-Aldrich
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MISSION® siRNA - SIHK2324 from Sigma-Aldrich
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MISSION® siRNA - SIHK2325 from Sigma-Aldrich
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MISSION® siRNA - SIHK2326 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2495 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2495 from Sigma-Aldrich
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TRIB1 siRNA (Human) - CRH6910 from Cohesion Biosciences
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TRIB1 - MBS8233701 from MyBioSource
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shRNA set against Human TRIB1 (NM_025195.2) - SHH434316 from Creative biogene
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shRNA set against Human TRIB1(NM_025195.2) - SHL092964 from Creative biogene
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TRB-1 CRISPR/Cas9 KO Plasmid (h2) - sc-405781-KO-2 from Santa Cruz Biotechnology
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TRB-1 HDR Plasmid (h2) - sc-405781-HDR-2 from Santa Cruz Biotechnology
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Human TRIB1 siRNA - orb267412 from Biorbyt
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