Gene Symbol | ME1 |
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Entrez Gene | 4199 |
Alt Symbol | HUMNDME, MES |
Species | Human |
Gene Type | protein-coding |
Description | malic enzyme 1, NADP(+)-dependent, cytosolic |
Other Description | Malic enzyme, cytoplasmic|NADP-ME|NADP-dependent malic enzyme|malate dehydrogenase|malic enzyme 1, soluble|pyruvic-malic carboxylase |
Swissprots | Q9H1W3 Q53F72 Q16855 Q16797 Q5VWA2 P48163 B4DZ70 Q9BWX8 Q9UIY4 |
Accessions | AAD15054 CAA02318 EAW48664 P48163 AJ420574 AK223417 BAD97137 AK289783 BAF82472 AK301875 BAG63311 AK302777 BAG63982 BC017403 AAH17403 BC025246 AAH25246 BX376125 DA520723 DQ892155 ABM83081 EU176687 ABW03488 L34035 AAB01380 U43944 AAC50613 X77244 CAA54460 XM_011535836 XP_011534138 NM_002395 NP_002386 |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:8187880}. |
Tissue Specificity | Expressed in all tissues tested including liver, placenta and white adipose tissue. {ECO:0000269|PubMed:7622060, ECO:0000269|PubMed:8187880}. |
Top Pathways | PPAR signaling pathway, Pyruvate metabolism, Carbon metabolism |
ME1 CRISPR/Cas9 KO Plasmid (h) - sc-401587 from Santa Cruz Biotechnology
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ME1 HDR Plasmid (h) - sc-401587-HDR from Santa Cruz Biotechnology
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ME1 Double Nickase Plasmid (h) - sc-401587-NIC from Santa Cruz Biotechnology
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ME1 Double Nickase Plasmid (h2) - sc-401587-NIC-2 from Santa Cruz Biotechnology
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ME1 CRISPR Activation Plasmid (h) - sc-401587-ACT from Santa Cruz Biotechnology
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ME1 CRISPR Activation Plasmid (h2) - sc-401587-ACT-2 from Santa Cruz Biotechnology
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ME1 Lentiviral Activation Particles (h) - sc-401587-LAC from Santa Cruz Biotechnology
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ME1 Lentiviral Activation Particles (h2) - sc-401587-LAC-2 from Santa Cruz Biotechnology
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ME1 siRNA (h) - sc-95470 from Santa Cruz Biotechnology
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ME1 shRNA Plasmid (h) - sc-95470-SH from Santa Cruz Biotechnology
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ME1 shRNA (h) Lentiviral Particles - sc-95470-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU032791 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN13149 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13149 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09764 from Sigma-Aldrich
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ME1 siRNA (Human) - CRH2855 from Cohesion Biosciences
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shRNA set against Human ME1 (NM_002395.4) - SHH339727 from Creative biogene
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Human ME1 siRNA - orb263357 from Biorbyt
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ME1 shRNA Plasmid (Human) - CHH2855 from Cohesion Biosciences
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ME1 miRNA 3'UTR clone - MiUTR3H-01376 from Creative biogene
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