Gene Symbol | AK8 |
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Entrez Gene | 158067 |
Alt Symbol | AK 8, C9orf98, DDX31 |
Species | Human |
Gene Type | protein-coding |
Description | adenylate kinase 8 |
Other Description | ATP-AMP transphosphorylase 8|putative adenylate kinase-like protein C9orf98 |
Swissprots | Q8N9W9 Q96MA6 A8K821 |
Accessions | EAW88012 EAW88013 EAW88014 EAW88015 EAW88016 EAW88017 Q96MA6 AK057266 BAB71402 AK093333 BAC04134 AK093446 BAC04168 AK292186 BAF84875 BC034776 AAH34776 BC037402 BC050576 AAH50576 HQ447306 ADQ31793 XM_005272169 XP_005272226 XM_006716964 XP_006717027 XM_006716965 XP_006717028 XM_011518277 XP_011516579 XM_011518278 XP_011516580 XM_011518279 XP_011516581 XM_011518280 XP_011516582 XR_929719 NM_152572 NP_689785 |
Function | Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP. Also displays broad nucleoside diphosphate kinase activity. {ECO:0000269|PubMed:21080915, ECO:0000269|PubMed:23416111}. |
Subcellular Location | Cytoplasm, cytosol {ECO:0000269|PubMed:21080915}. |
Top Pathways | Purine metabolism |
AK8 CRISPR/Cas9 KO Plasmid (h) - sc-409383 from Santa Cruz Biotechnology
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AK8 HDR Plasmid (h) - sc-409383-HDR from Santa Cruz Biotechnology
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AK8 Double Nickase Plasmid (h) - sc-409383-NIC from Santa Cruz Biotechnology
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AK8 Double Nickase Plasmid (h2) - sc-409383-NIC-2 from Santa Cruz Biotechnology
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AK8 CRISPR Activation Plasmid (h) - sc-409383-ACT from Santa Cruz Biotechnology
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AK8 CRISPR Activation Plasmid (h2) - sc-409383-ACT-2 from Santa Cruz Biotechnology
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AK8 Lentiviral Activation Particles (h) - sc-409383-LAC from Santa Cruz Biotechnology
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AK8 Lentiviral Activation Particles (h2) - sc-409383-LAC-2 from Santa Cruz Biotechnology
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AK8 siRNA (h) - sc-92699 from Santa Cruz Biotechnology
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AK8 shRNA Plasmid (h) - sc-92699-SH from Santa Cruz Biotechnology
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AK8 shRNA (h) Lentiviral Particles - sc-92699-V from Santa Cruz Biotechnology
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C9orf98 RNAi - H00158067-R01V from Novus Biologicals
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C9orf98 RNAi - H00158067-R02 from Novus Biologicals
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MISSION® esiRNA - EHU038911 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3000 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3000 from Sigma-Aldrich
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AK8 siRNA (Human) - CRJ5849 from Cohesion Biosciences
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AK8 - MBS8207818 from MyBioSource
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shRNA set against Human AK8 (NM_152572.2) - SHH234154 from Creative biogene
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shRNA set against Human C9orf98(NM_152572.2) - SHG121699 from Creative biogene
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Human AK8 siRNA - orb276350 from Biorbyt
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AK8 shRNA Plasmid (Human) - CHJ5849 from Cohesion Biosciences
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AK8 miRNA 3'UTR clone - MiUTR1H-01555 from Creative biogene
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